Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.70 |
| ▸ | PPARG | P37231 | 2/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.68 |
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | PLG | P00747 | 3/20 | 0.64 |
| ▸ | ELANE | P08246 | 2/20 | 0.64 |
| ▸ | CREB1 | P16220 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17523234 | 0.90 | BCHE (0.82) | L3MBTL1MAPTABCB1PPARGABCG2 | |
| SCHEMBL29979584 | 0.89 | L3MBTL1 (0.79) | L3MBTL1MAPTABCB1PPARGABCG2 | |
| SCHEMBL27963408 | 0.87 | L3MBTL1 (0.77) | L3MBTL1MAPTABCB1PPARGABCG2 | |
| SCHEMBL19267888 | 0.87 | L3MBTL1 (0.77) | L3MBTL1MAPTABCB1PPARGABCG2 | |
| SCHEMBL30376090 | 0.87 | L3MBTL1 (0.77) | L3MBTL1MAPTABCB1PPARGABCG2 | |
| SCHEMBL4145144 | 0.85 | L3MBTL1 (0.73) | L3MBTL1MAPTABCB1PPARGABCG2 | |
| SCHEMBL8066758 | 0.84 | L3MBTL1 (0.72) | L3MBTL1MAPTABCB1PPARGABCG2 | |
| SCHEMBL13741293 | 0.84 | L3MBTL1 (0.71) | L3MBTL1MAPTABCB1PPARGABCG2 | |
| SCHEMBL5792042 | 0.83 | MAPT (0.91) | L3MBTL1MAPTABCB1PPARGABCG2 | |
| SCHEMBL738489 | 0.83 | MEN1 (0.71) | L3MBTL1ABCB1ABCG2ACHECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605241-B2 | Synthesis of inhibitors of p90Rsk | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2009-10-20 | — | — | US | disclosed |
| US-7605241-B2 | Synthesis of inhibitors of p90Rsk | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2009-10-20 | — | — | US | disclosed |
| US-20080269144-A1 | Synthesis of Inhibitors of P90Rsk | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2008-10-30 | — | — | US | disclosed |
| US-20080269144-A1 | Synthesis of Inhibitors of P90Rsk | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269144-A1 | Synthesis of Inhibitors of P90Rsk | RAF1, KSR1, STK10 | L3MBTL1 1916/4885MAPT 4264/4885ABCB1 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.