Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | USP10 | Q14694 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GALR2 | O43603 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790681 | 0.90 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2USP10TDP1HPGD | |
| SCHEMBL10789604 | 0.90 | USP10 (0.57) | ALDH1A1SMN1; SMN2GAAUSP10TDP1 | |
| SCHEMBL10789597 | 0.86 | USP10 (0.46) | ALDH1A1SMN1; SMN2GAAUSP10TDP1 | |
| SCHEMBL10789577 | 0.85 | USP10 (0.45) | ALDH1A1SMN1; SMN2GAAUSP10TDP1 | |
| SCHEMBL2724028 | 0.85 | TDP1 (0.62) | ALDH1A1SMN1; SMN2TDP1HPGDPOLB | |
| SCHEMBL28134455 | 0.84 | MEN1 (0.57) | HSP90AA1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL21395564 | 0.84 | LMNA (0.56) | ALDH1A1SMN1; SMN2GAAUSP10TDP1 | |
| SCHEMBL21707869 | 0.84 | MAPT (0.58) | ALDH1A1SMN1; SMN2GAAUSP10TDP1 | |
| SCHEMBL10785520 | 0.83 | MAPT (0.52) | ALDH1A1SMN1; SMN2GAAUSP10TDP1 | |
| SCHEMBL3889423 | 0.82 | MEN1 (0.55) | TDP1POLBSIRT6KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935221-B1 | QUINOLONE DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2018-02-07 | — | — | EP | disclosed |
| CN-104903295-B | Carbostyril derivative | 卡迪拉保健有限公司 | 2017-09-01 | — | — | CN | disclosed |
| US-9394300-B2 | Quinolone derivatives | CADILA HEALTHCARE LIMITED (IN) | 2016-07-19 | — | — | US | disclosed |
| EP-2935221-A1 | NOVEL QUINOLONE DERIVATIVES | Cadila Healthcare Limited (IN) | 2015-10-28 | — | — | EP | disclosed |
| US-20150299193-A1 | NOVEL QUINOLONE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2015-10-22 | — | — | US | disclosed |
| WO-2014102818-A1 | NOVEL QUINOLONE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2014-07-03 | — | — | WO | disclosed |
| US-7569725-B2 | 2-[(3-chloro-4-hydroxybenzoyl)amino]-N-[2-(2-methoxyphenyl)ethyl]-5-phenoxybenzamide; therapeutic use as anti-cancer agents, as well as other therapeutic agents, for example, as anti-fertility agents | BRITSOL-MYERS SQUIBB COMPANY (US) | 2009-08-04 | — | — | US | disclosed |
| US-7569725-B2 | 2-[(3-chloro-4-hydroxybenzoyl)amino]-N-[2-(2-methoxyphenyl)ethyl]-5-phenoxybenzamide; therapeutic use as anti-cancer agents, as well as other therapeutic agents, for example, as anti-fertility agents | BRITSOL-MYERS SQUIBB COMPANY (US) | 2009-08-04 | — | — | US | disclosed |
| US-7569725-B2 | 2-[(3-chloro-4-hydroxybenzoyl)amino]-N-[2-(2-methoxyphenyl)ethyl]-5-phenoxybenzamide; therapeutic use as anti-cancer agents, as well as other therapeutic agents, for example, as anti-fertility agents | BRITSOL-MYERS SQUIBB COMPANY (US) | 2009-08-04 | — | — | US | disclosed |
| US-20060135619-A1 | 2-[(3-chloro-4-hydroxybenzoyl)amino]-N-[2-(2-methoxyphenyl)ethyl]-5-phenoxybenzamide; therapeutic use as anti-cancer agents, as well as other therapeutic agents, for example, as anti-fertility agents | BRISTOL-MYERS SQUIBB COMPANY | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299193-A1 | NOVEL QUINOLONE DERIVATIVES | NQO2, UGT1A1, CYP11B2 | ALDH1A1 2214/4885SMN1; SMN2 3982/4885PTGS2 848/4885 |
| US-20060135619-A1 | 2-[(3-chloro-4-hydroxybenzoyl)amino]-N-[2-(2-methoxyphenyl)ethyl]-5-phenoxybenzamide; therapeutic use as anti-cancer agents, as well as other therapeutic agents, for example, as anti-fertility agents | NASP, BRDT, ACR | ALDH1A1 506/4885SMN1; SMN2 3983/4885PTGS2 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.