SCHEMBL4270475

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4273489	0.93	S1PR1 (0.41)	IDO1TDO2S1PR1S1PR3S1PR5
	SCHEMBL13701426	0.93	S1PR1 (0.43)	IDO1TDO2S1PR1S1PR3S1PR5
	SCHEMBL4280683	0.92	CTNNB1 (0.43)	IDO1TDO2NPC1PKMRAB9A
	SCHEMBL4276073	0.92	GAA (0.38)	IDO1TDO2S1PR1NPC1PKM
	SCHEMBL4276119	0.91	CTNNB1 (0.41)	IDO1TDO2S1PR1S1PR3S1PR5
	SCHEMBL19199080	0.89	S1PR1 (0.39)	IDO1TDO2S1PR1S1PR3S1PR5
	SCHEMBL4282846	0.89	MAPT (0.41)	IDO1TDO2S1PR1S1PR3S1PR5
	SCHEMBL4281082	0.88	MAPT (0.43)	NPC1PKMRAB9APARP1PTGES
	SCHEMBL4278967	0.88	SMN1; SMN2 (0.41)	S1PR1S1PR3S1PR5NPC1PKM
	SCHEMBL4275723	0.88	S1PR1 (0.38)	IDO1TDO2S1PR1S1PR3S1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.