SCHEMBL4280683

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4281082	0.94	MAPT (0.43)	RAB9ANPC1PKMALDH1A1HTT
	SCHEMBL4271880	0.93	TSHR (0.41)	CTNNB1WNT3ARAB9ANPC1PKM
	SCHEMBL4270475	0.92	IDO1 (0.41)	CTNNB1WNT3ARAB9ANPC1PKM
	SCHEMBL4280738	0.92	CTNNB1 (0.39)	CTNNB1WNT3ARAB9ANPC1PKM
	SCHEMBL29813417	0.92	CTNNB1 (0.39)	CTNNB1WNT3ARAB9ANPC1PKM
	SCHEMBL4272471	0.92	NPC1 (0.42)	CTNNB1WNT3ARAB9ANPC1PKM
	SCHEMBL13701440	0.92	CTNNB1 (0.45)	CTNNB1WNT3ARAB9ANPC1ALDH1A1
	SCHEMBL4279520	0.92	CTNNB1 (0.38)	CTNNB1WNT3ARAB9ANPC1PKM
	SCHEMBL4276073	0.92	GAA (0.38)	CTNNB1WNT3ARAB9ANPC1PKM
	SCHEMBL4280709	0.92	LCLAT1 (0.39)	CTNNB1WNT3ARAB9ANPC1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.