SCHEMBL4281082

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4280683	0.94	CTNNB1 (0.43)	MAPTKMT2AALDH1A1NPC1RAB9A
	SCHEMBL4272471	0.92	NPC1 (0.42)	MAPTKMT2AMEN1SMN1; SMN2ALDH1A1
	SCHEMBL8237292	0.89	SMN1; SMN2 (0.43)	MAPTKMT2AMEN1SMN1; SMN2ALDH1A1
	SCHEMBL4271880	0.89	TSHR (0.41)	MAPTKMT2AMEN1SMN1; SMN2ALDH1A1
	SCHEMBL4280738	0.88	CTNNB1 (0.39)	MAPTKMT2AMEN1SMN1; SMN2ALDH1A1
	SCHEMBL29813417	0.88	CTNNB1 (0.39)	MAPTKMT2AMEN1SMN1; SMN2ALDH1A1
	SCHEMBL4270475	0.88	IDO1 (0.41)	MAPTKMT2AMEN1SMN1; SMN2ALDH1A1
	SCHEMBL4282846	0.88	MAPT (0.41)	MAPTKMT2AMEN1SMN1; SMN2ALDH1A1
	SCHEMBL4279520	0.88	CTNNB1 (0.38)	MAPTSMN1; SMN2NPC1RAB9APKM
	SCHEMBL4276073	0.88	GAA (0.38)	MAPTALDH1A1GAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.