SCHEMBL4270793

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4273123	0.95	HPGD (0.51)	HPGDLMNAALDH1A1MAPK1SMN1; SMN2
	SCHEMBL4280806	0.93	HPGD (0.49)	HPGDLMNAALDH1A1MAPK1SMN1; SMN2
	SCHEMBL4280252	0.92	LMNA (0.50)	HPGDLMNAALDH1A1MAPK1SMN1; SMN2
	SCHEMBL4273072	0.90	HPGD (0.45)	HPGDLMNAALDH1A1MAPK1SMN1; SMN2
	SCHEMBL4275015	0.88	HPGD (0.50)	HPGDLMNAALDH1A1MAPK1SMN1; SMN2
	SCHEMBL4275305	0.87	DHODH (0.46)	HPGDLMNAALDH1A1MAPK1SMN1; SMN2
	SCHEMBL4276907	0.86	S1PR1 (0.47)	HPGDLMNAALDH1A1MAPK1SMN1; SMN2
	SCHEMBL4278342	0.86	HPGD (0.50)	HPGDLMNAALDH1A1MAPK1SMN1; SMN2
	SCHEMBL4279613	0.86	PDE4B (0.48)	HPGDLMNAALDH1A1MAPK1TP53
	SCHEMBL4270560	0.86	HPGD (0.43)	HPGDLMNAALDH1A1SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.