SCHEMBL4276907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4273113	0.95	HPGD (0.44)	S1PR1TP53MAPTHPGDKDM4E
	SCHEMBL4284184	0.93	LCLAT1 (0.42)	S1PR1TP53MAPTHPGDKDM4E
	SCHEMBL4276055	0.93	LCLAT1 (0.43)	S1PR1TP53MAPTHPGDKDM4E
	SCHEMBL4271158	0.93	PTGS2 (0.45)	S1PR1TP53MAPTHPGDKDM4E
	SCHEMBL4280252	0.93	LMNA (0.50)	TP53MAPTHPGDKDM4EMAPK1
	SCHEMBL4273733	0.91	LCLAT1 (0.45)	S1PR1TP53MAPTHPGDKDM4E
	SCHEMBL4275646	0.91	PDE4B (0.43)	S1PR1TP53MAPTHPGDKDM4E
	SCHEMBL4280294	0.89	LCLAT1 (0.43)	TP53MAPTHPGDLMNALCLAT1
	SCHEMBL4269836	0.88	GSK3B (0.40)	MAPTHPGDKDM4EALDH1A1LMNA
	SCHEMBL4275015	0.87	HPGD (0.50)	TP53MAPTHPGDKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.