SCHEMBL4280252

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4276907	0.93	S1PR1 (0.47)	LMNAHPGDALDH1A1MAPK1HTT
	SCHEMBL4270793	0.92	HPGD (0.52)	LMNAHPGDALDH1A1MAPK1HTT
	SCHEMBL4273113	0.91	HPGD (0.44)	LMNAHPGDALDH1A1MAPK1HTT
	SCHEMBL4273072	0.90	HPGD (0.45)	LMNAHPGDALDH1A1MAPK1HTT
	SCHEMBL4273123	0.90	HPGD (0.51)	LMNAHPGDALDH1A1MAPK1HTT
	SCHEMBL4276055	0.90	LCLAT1 (0.43)	LMNAHPGDALDH1A1MAPK1HTT
	SCHEMBL4284184	0.88	LCLAT1 (0.42)	LMNAHPGDALDH1A1MAPK1HTT
	SCHEMBL4280806	0.88	HPGD (0.49)	LMNAHPGDALDH1A1MAPK1HTT
	SCHEMBL4273733	0.88	LCLAT1 (0.45)	LMNAHPGDALDH1A1MAPK1HTT
	SCHEMBL4271158	0.88	PTGS2 (0.45)	LMNAHPGDALDH1A1MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.