SCHEMBL4270863

SCHEMBL4270863

CCOc1nc(OCC)c(C)[nH]1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
HCAR2 Q8TDS4 1/20 0.34
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MAT2A P31153 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9369338 0.65 LRRK2 (0.33) LRRK2MAT2AKDM4E
SCHEMBL1890353 0.64 MAPT (0.50) KDM4CHCAR2KDM4E
SCHEMBL12936238 0.64 HPGD (0.31) LRRK2MEN1KMT2A
SCHEMBL22049325 0.63 KDM4C (0.44) KDM4CHCAR2MAT2AKDM4E
SCHEMBL7268449 0.63 CA12 (0.34) LRRK2
SCHEMBL20436746 0.62 KDM4C (0.43) KDM4CMEN1KMT2AKDM4E
SCHEMBL4365099 0.62 CBFB (0.49)
SCHEMBL2675687 0.61 DDAH1 (0.56) MEN1KMT2AKDM4E
SCHEMBL5701886 0.61 ALDH1A1 (0.47) KDM4CHCAR2KDM4E
SCHEMBL4362603 0.61 KDM4C (0.42) LRRK2KDM4CHCAR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed