Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 4/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271073 | 0.81 | HSD17B1 (0.52) | TRPV3RAB9A | |
| SCHEMBL2953474 | 0.80 | MEN1 (0.60) | TRPV3MEN1RAB9AKMT2ATHRB | |
| SCHEMBL4591178 | 0.79 | CNR2 (0.48) | TRPV3NOTUM | |
| SCHEMBL17595532 | 0.79 | KMO (0.48) | TRPV3MEN1KMT2ATHRBTGFBR1 | |
| SCHEMBL29897575 | 0.79 | KMO (0.48) | TRPV3MEN1KMT2ATHRBTGFBR1 | |
| SCHEMBL16588099 | 0.77 | CCR1 (0.48) | TRPV3MEN1RAB9AKMT2ATHRB | |
| SCHEMBL24701007 | 0.76 | CYP2A6 (0.57) | IRAK4 | |
| SCHEMBL21790698 | 0.75 | GABRG2 (0.50) | RAB9A | |
| SCHEMBL9145225 | 0.75 | CCR1 (0.46) | TRPV3MEN1RAB9AKMT2ATHRB | |
| SCHEMBL16396753 | 0.73 | AOC3 (0.45) | TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094662-B1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC (JP) | 2012-04-11 | — | — | EP | disclosed |
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |