SCHEMBL4271269

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17037225	0.82	PDE4A (0.53)	ALDH1A1KDM4ETSHRHSD17B10MAPT
	SCHEMBL17037226	0.81	ALDH1A1 (0.52)	ALDH1A1KDM4ETSHRHSD17B10MAPT
	SCHEMBL17037227	0.81	PDE4A (0.52)	ALDH1A1KDM4ETSHRHSD17B10MAPT
	SCHEMBL4284461	0.81	KDM4E (0.44)	ALDH1A1KDM4ETSHRHSD17B10MAPT
	SCHEMBL4284454	0.81	KDM4E (0.44)	ALDH1A1KDM4ETSHRHSD17B10MAPT
	SCHEMBL4269852	0.81	KDM4E (0.53)	ALDH1A1KDM4ETSHRHSD17B10MAPT
	SCHEMBL17243832	0.81	TSHR (0.53)	ALDH1A1KDM4ETSHRHSD17B10MAPT
	SCHEMBL4270604	0.81	TSHR (0.53)	ALDH1A1KDM4ETSHRHSD17B10MAPT
	SCHEMBL4284492	0.81	KDM4E (0.44)	ALDH1A1KDM4ETSHRHSD17B10MAPT
	SCHEMBL4284427	0.78	HSD17B10 (0.50)	ALDH1A1KDM4EHSD17B10MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.