SCHEMBL4284492

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4271269	0.81	ALDH1A1 (0.53)	KDM4ESMN1; SMN2HPGDHSD17B10LMNA
	SCHEMBL4271902	0.81	KDM4E (0.44)	KDM4ESMN1; SMN2NPSR1HPGDHSD17B10
	SCHEMBL4275021	0.81	KDM4E (0.44)	KDM4ESMN1; SMN2NPSR1HPGDHSD17B10
	SCHEMBL4284427	0.79	HSD17B10 (0.50)	KDM4ESMN1; SMN2HPGDHSD17B10LMNA
	SCHEMBL4270515	0.79	ALDH1A1 (0.41)	KDM4ESMN1; SMN2NPSR1HPGDHSD17B10
	SCHEMBL4277046	0.77	PPARG (0.42)	KDM4ESMN1; SMN2HPGDHSD17B10LMNA
	SCHEMBL15450565	0.77	HPGD (0.40)	KDM4ESMN1; SMN2HPGDHSD17B10LMNA
	SCHEMBL4271845	0.77	FPR2 (0.41)	FPR2
	SCHEMBL4271851	0.77	FPR2 (0.41)	FPR2
	SCHEMBL4275001	0.76	KDM4E (0.39)	KDM4ESMN1; SMN2NPSR1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.