Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 11/20 | 0.77 |
| ▸ | THRB | P10828 | 11/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.77 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.77 |
| ▸ | PGR | P06401 | 1/20 | 0.77 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.77 |
| ▸ | AR | P10275 | 1/20 | 0.77 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.67 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.67 |
| ▸ | PCNA | P12004 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4273581 | 0.87 | THRA (0.57) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL4898980 | 0.87 | THRA (1.00) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL4271148 | 0.87 | THRA (0.57) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL4269700 | 0.86 | FFAR1 (0.70) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL4266556 | 0.85 | FFAR1 (0.63) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL4271200 | 0.83 | MRGPRX4 (0.59) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL1998296 | 0.80 | FFAR1 (1.00) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL4887059 | 0.80 | THRB (0.80) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL4280680 | 0.80 | FFAR1 (0.60) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL4898421 | 0.80 | THRA (0.77) | THRATHRBESR1NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066362-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | Boston Scientific Limited (BB) | 2009-06-10 | — | — | EP | claimed |
| WO-2008033198-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | BOSTON SCIENTIFIC LIMITED (BB) | 2008-03-20 | — | — | WO | claimed |
| US-20080064848-A1 | Radiopaque amide polymers and medical devices formed thereof | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-03-13 | — | — | US | claimed |
| US-6638977-B1 | Biaryl and benzyl ethers and thioethers | CORVAS INTERNATIONAL, INC. | 2003-10-28 | — | — | US | claimed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | claimed |
| US-8507639-B2 | Polyamide block polymers containing iodoarylcarboxyl pendant groups and modified poly(meth)acrylamide; coupling; for tracking movement of a catheter through the body or inflation of balloon at site | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| EP-2066362-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | Boston Scientific Limited (BB) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008033198-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | BOSTON SCIENTIFIC LIMITED (BB) | 2008-03-20 | — | — | WO | disclosed |
| US-20080064848-A1 | Radiopaque amide polymers and medical devices formed thereof | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |