Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666203 | 0.97 | THRB (0.50) | THRBLMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL14370289 | 0.97 | THRB (0.50) | THRBLMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL17301297 | 0.97 | THRB (0.50) | THRBLMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL22245659 | 0.97 | THRB (0.50) | THRBLMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL12510630 | 0.96 | HTT (0.49) | THRBLMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL12794263 | 0.96 | HTT (0.49) | THRBLMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL12768610 | 0.96 | HTT (0.49) | THRBLMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL14280595 | 0.96 | HTT (0.49) | THRBLMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL223268 | 0.96 | HTT (0.49) | THRBLMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL18470122 | 0.95 | THRB (0.55) | THRBLMNATSHRCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3088426-A1 | COMPOUND CONTAINING MESOGENIC GROUP, AND MIXTURE, COMPOSITION, AND OPTICALLY ANISOTROPIC BODY USING SAID COMPOUND | DIC Corporation (JP) | 2016-11-02 | — | — | EP | disclosed |
| US-8613868-B2 | Mesogenic stabilizers | TRANSITIONS OPTICAL, INC (US) | 2013-12-24 | — | — | US | disclosed |
| WO-2013022610-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2013-02-14 | — | — | WO | disclosed |
| US-20120021144-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021144-A1 | MESOGENIC STABILIZERS | C1S, C5, CCNL2 | THRB 3981/4885LMNA 260/4885TSHR 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.