SCHEMBL8666203

SCHEMBL8666203

C=CC(=O)OCCCCOc1ccc(C(=O)Oc2ccc(O)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
LMNA P02545 3/20 0.48
TSHR P16473 3/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2D6 P10635 2/20 0.48
CYP2C19 P33261 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
ESR1 P03372 1/20 0.48
MAPK1 P28482 1/20 0.48
NR1H2 P55055 1/20 0.48
RNASEL Q05823 1/20 0.48
CYP3A4 P08684 2/20 0.47
NPC1 O15118 2/20 0.47
HTT P42858 2/20 0.47
CYP2C9 P11712 1/20 0.47
ALDH1A1 P00352 2/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
PRSS1 P07477 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22245659 1.00 THRB (0.50) THRBLMNATSHRCYP1A2CYP2D6
SCHEMBL17301297 1.00 THRB (0.50) THRBLMNATSHRCYP1A2CYP2D6
SCHEMBL14370289 1.00 THRB (0.50) THRBLMNATSHRCYP1A2CYP2D6
SCHEMBL223268 0.99 HTT (0.49) THRBLMNATSHRCYP1A2CYP2D6
SCHEMBL12510630 0.99 HTT (0.49) THRBLMNATSHRCYP1A2CYP2D6
SCHEMBL12768610 0.99 HTT (0.49) THRBLMNATSHRCYP1A2CYP2D6
SCHEMBL12794263 0.99 HTT (0.49) THRBLMNATSHRCYP1A2CYP2D6
SCHEMBL14280595 0.99 HTT (0.49) THRBLMNATSHRCYP1A2CYP2D6
SCHEMBL427272 0.97 THRB (0.50) THRBLMNATSHRCYP1A2CYP2D6
SCHEMBL711551 0.95 HTT (0.46) THRBLMNATSHRCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10035956-B2 Compound and liquid-crystal composition employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2018-07-31 US disclosed
US-20170174995-A1 COMPOUND AND LIQUID-CRYSTAL COMPOSITION EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-06-22 US disclosed
US-20170174994-A1 COMPOUND AND LIQUID CRYSTAL COMPOSITION EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-06-22 US disclosed
US-9464228-B2 Liquid crystal composition, method for manufacturing the same, and film FUJIFILM CORPORATION (JP) 2016-10-11 US disclosed
US-9464228-B2 Liquid crystal composition, method for manufacturing the same, and film FUJIFILM CORPORATION (JP) 2016-10-11 US disclosed
US-20150191652-A1 LIQUID CRYSTAL COMPOSITION, METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US disclosed
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US disclosed
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US disclosed
US-20150191652-A1 LIQUID CRYSTAL COMPOSITION, METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US disclosed
US-7988882-B2 Polymerizable liquid crystal compound, phase difference film and liquid crystal display using the same FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-20100047478-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, PHASE DIFFERENCE FILM AND LIQUID CRYSTAL DISPLAY USING THE SAME FUJIFILM CORPORATION (JP) 2010-02-25 US disclosed
US-20070286968-A1 Compound, liquid crystal composition, and their applications FUJIFILM CORPORATION (JP) 2007-12-13 US disclosed
US-20070286968-A1 Compound, liquid crystal composition, and their applications FUJIFILM CORPORATION (JP) 2007-12-13 US disclosed
US-5833880-A MIXTURE POLYMERIZABLE BY FREE RADICAL OR IONIC POLYMERIZATION BASF AKTIENGESELLSCHAFT (DE) 1998-11-10 US disclosed
EP-0749466-B1 NOVEL POLYMERISABLE LIQUID-CRYSTALLINE COMPOUNDS BASF AG (DE) 1997-11-12 EP disclosed
EP-0749466-A1 NOVEL POLYMERISABLE LIQUID-CRYSTALLINE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1996-12-27 EP disclosed
WO-1995024454-A1 NOVEL POLYMERISABLE LIQUID-CRYSTALLINE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1995-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM PYM1, C9, LANCL2 THRB 4118/4885LMNA 210/4885TSHR 4393/4885
US-20100047478-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, PHASE DIFFERENCE FILM AND LIQUID CRYSTAL DISPLAY USING THE SAME SP1, PAXBP1, CCNT1 THRB 4226/4885LMNA 431/4885TSHR 4351/4885
US-20170174995-A1 COMPOUND AND LIQUID-CRYSTAL COMPOSITION EMPLOYING THE SAME ZYX, ZRANB2, CXXC4 THRB 2214/4885LMNA 430/4885TSHR 3390/4885
US-20170174994-A1 COMPOUND AND LIQUID CRYSTAL COMPOSITION EMPLOYING THE SAME ZYX, ZRANB2, CXXC4 THRB 2168/4885LMNA 624/4885TSHR 3097/4885
US-10035956-B2 Compound and liquid-crystal composition employing the same ZYX, ZRANB2, CXXC4 THRB 2214/4885LMNA 430/4885TSHR 3390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.