SCHEMBL4273103

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4280658	0.88	HPGD (0.49)	RAB9AKDM4EALDH1A1HSD17B10HPGD
	SCHEMBL4280795	0.87	KDM4E (0.54)	APPNPC1RAB9AKDM4EALDH1A1
	SCHEMBL4271285	0.85	KDM4E (0.52)	APPNPC1RAB9AKDM4EALDH1A1
	SCHEMBL4277058	0.83	ALDH1A1 (0.45)	NPC1RAB9AKDM4EALDH1A1HSD17B10
	SCHEMBL4270659	0.83	HTT (0.47)	RAB9AKDM4EALDH1A1HSD17B10HPGD
	SCHEMBL4639757	0.82	MEN1 (0.52)	APPNPC1RAB9AKDM4EALDH1A1
	SCHEMBL4270615	0.82	SMPD1 (0.48)	KDM4EALDH1A1TSHRHSD17B10HPGD
	SCHEMBL4277665	0.81	KDM4E (0.47)	APPKDM4EALDH1A1TSHRHSD17B10
	SCHEMBL4639334	0.81	FFAR1 (0.55)	KDM4EALDH1A1TSHRHSD17B10HPGD
	SCHEMBL4271756	0.80	TSHR (0.48)	KDM4EALDH1A1TSHRHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.