SCHEMBL4273248

SCHEMBL4273248

N#CC(C#N)=C1CCC2(CC1)CCC(=C(C#N)C#N)CC2

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 1/20 0.39
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
GPR35 Q9HC97 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2786474 0.80 ALDH1A1 (0.46) ALDH1A1HSD17B10DRD2DRD3
SCHEMBL19973082 0.80 ALDH1A1 (0.33) ALDH1A1HSD17B10DRD2DRD3GPR35
SCHEMBL19983784 0.77 ALDH1A1 (0.35) ALDH1A1HSD17B10DRD2DRD3GPR35
SCHEMBL5508352 0.75 ALDH1A1 (0.60) ALDH1A1HSD17B10DRD2DRD3GPR35
Hydrochloric Acid SCHEMBL11032285 0.75 ALDH1A1 (0.43) ALDH1A1HSD17B10DRD2DRD3
SCHEMBL13349939 0.72 ALDH1A1 (0.64) ALDH1A1HSD17B10DRD2DRD3GPR35
SCHEMBL3708976 0.72 ALDH1A1 (0.64) ALDH1A1HSD17B10DRD2DRD3GPR35
SCHEMBL19973070 0.72 ALDH1A1 (0.64) ALDH1A1HSD17B10DRD2DRD3GPR35
SCHEMBL4048255 0.72 DRD2 (0.33) ALDH1A1HSD17B10DRD2DRD3GPR35
SCHEMBL19973072 0.68 ALDH1A1 (0.39) ALDH1A1HSD17B10DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7557372-B2 Memory devices based on electric field programmable films THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-07-07 US claimed
US-20080095924-A1 Memory devices based on electric field programmable films ROHM AND HAAS COMPANY (US) 2008-04-24 US claimed
US-7274035-B2 Memory devices based on electric field programmable films THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-09-25 US claimed
EP-1744370-A2 Electric field programmable films and memory devices based thereon Rohm and Haas Electronic Materials LLC (US) 2007-01-17 EP claimed
US-20070009201-A1 Electric field programmable films and memory devices based thereon ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2007-01-11 US claimed
US-20050211978-A1 Memory devices based on electric field programmable films BU LUJIA 2005-09-29 US claimed
US-20050058009-A1 Memory devices based on electric field programmable films UNITED STATES AIR FORCE 2005-03-17 US claimed
EP-1513159-A2 Memory devices based on electric field programmable films THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-03-09 EP claimed
US-7557372-B2 Memory devices based on electric field programmable films THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-07-07 US disclosed
EP-1580825-B1 Memory devices based on electric field programmable films ROHM & HAAS (US) 2008-06-11 EP disclosed
US-20080095924-A1 Memory devices based on electric field programmable films ROHM AND HAAS COMPANY (US) 2008-04-24 US disclosed
EP-1901291-A2 Methods for writing and reading information and devices based thereon Rohm and Haas Company (US) 2008-03-19 EP disclosed
US-20080062853-A1 Methods for writing and reading information and devices based thereon BU LUJIA 2008-03-13 US disclosed
US-20080049590-A1 Devices and methods for writing and reading information BU LUJIA 2008-02-28 US disclosed
US-20070009821-A1 Devices containing multi-bit data CUTLER CHARLOTTE 2007-01-11 US disclosed
US-20070009201-A1 Electric field programmable films and memory devices based thereon ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2007-01-11 US disclosed
US-20050211978-A1 Memory devices based on electric field programmable films BU LUJIA 2005-09-29 US disclosed
EP-1580825-A1 Memory devices based on electric field programmable films ROHM AND HAAS COMPANY (US) 2005-09-28 EP disclosed
US-20050058009-A1 Memory devices based on electric field programmable films UNITED STATES AIR FORCE 2005-03-17 US disclosed
EP-1513159-A2 Memory devices based on electric field programmable films THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-03-09 EP disclosed