SCHEMBL4614541

SCHEMBL4614541

N#Cc1ccc(OCCCCC(=O)O)cc1

nearest known ligand 0.73

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.73
MMP3 P08254 4/20 0.64
HDAC1 Q13547 1/20 0.62
HDAC2 Q92769 1/20 0.62
PPARA Q07869 4/20 0.59
ALDH1A1 P00352 1/20 0.57
MAPT P10636 1/20 0.57
MMP1 P03956 1/20 0.55
MMP9 P14780 1/20 0.55
MMP13 P45452 1/20 0.55
ALB P02768 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.50
FFAR1 O14842 1/20 0.50
PLA2G4B P0C869 1/20 0.50
SERPINE1 P05121 2/20 0.49
PPARD Q03181 1/20 0.49
HRH3 Q9Y5N1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1139009 0.98 MMP2 (0.71) MMP2MMP3HDAC1HDAC2PPARA
SCHEMBL5516422 0.98 MMP2 (0.71) MMP2MMP3HDAC1HDAC2PPARA
SCHEMBL3952240 0.98 MMP2 (0.71) MMP2MMP3HDAC1HDAC2PPARA
SCHEMBL4273348 0.95 MMP2 (0.82) MMP2MMP3HDAC1HDAC2PPARA
SCHEMBL4654973 0.95 MMP2 (0.76) MMP2MMP3HDAC1HDAC2PPARA
SCHEMBL9128810 0.94 MMP2 (0.80) MMP2MMP3HDAC1HDAC2PPARA
SCHEMBL13862226 0.94 MMP2 (0.80) MMP2MMP3HDAC1HDAC2PPARA
SCHEMBL7520274 0.94 MMP2 (0.80) MMP2MMP3HDAC1HDAC2PPARA
SCHEMBL6252232 0.94 MMP2 (0.80) MMP2MMP3HDAC1HDAC2PPARA
SCHEMBL5097470 0.94 MMP2 (0.80) MMP2MMP3HDAC1HDAC2PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105051037-A Sphingosine-1-phosphate receptor agonists, method for the preparation thereof and pharmaceutical compositions comprising the same as active agent LG LIFE SCIENCES LTD 2015-11-11 CN disclosed
US-7425432-B2 Polyhydroxy alkanoate copolymer including within molecule unit having vinyl group or carboxyl group in side chain, and producing method therefor CANON KABUSHIKI KAISHA (JP) 2008-09-16 US disclosed
EP-1340776-B1 Polyhydroxyalkanoate and method for controlling molecular weight of polyhydroxyalkanoate constituted of units containing residue of phenyl-, thienyl-, or cyclohexyl-structure in side chain of molecule CANON KK (JP) 2008-02-06 EP disclosed
US-20060211100-A1 Novel polyhydroxy alkanoate copolymer including within molecule unit having vinyl group or carboxyl group in side chain, and producing method therefor CANON KABUSHIKI KAISHA (JP) 2006-09-21 US disclosed
WO-2004044213-A1 NOVEL POLYHYDROXY ALKANOATE COPOLYMER INCLUDING WITHIN MOLECULE UNIT HAVING VINYL GROUP OR CARBOXYL GROUP IN SIDE CHAIN, AND PRODUCING METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2004-05-27 WO disclosed
US-6649380-B1 Microorganism biosynthesis CANON KABUSHIKI KAISHA (JP) 2003-11-18 US disclosed
US-20030208028-A1 METHOD FOR CONTROLLING MOLECULAR WEIGHT OF POLYHYDROXYALKANOTE CONSTITUTED OF UNITS CONTAINING RESIDUE OF PHENYL-, THIENYL-, OR CYCLOHEXYL-STRUCTRUE IN SIDE CHAIN OF MOLECULE CANON KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
EP-1340776-A1 Method for controlling molecular weight of polyhydroxyalkanoate constituted of units containing residue of phenyl-, thienyl-, or cyclohexyl-structure in side chain of molecule CANON KABUSHIKI KAISHA (JP) 2003-09-03 EP disclosed
US-5574016-A Peptide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-11-12 US disclosed
EP-0513675-B1 New peptide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1996-09-11 EP disclosed
EP-0513675-A1 New peptide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-11-19 EP disclosed