Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274258 | 0.79 | TSHR (0.47) | CYP2A6CYP1A2TSHRACHEALDH1A1 | |
| SCHEMBL29776884 | 0.77 | TRPA1 (0.44) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL9363776 | 0.77 | TRPA1 (0.44) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL8967432 | 0.75 | TRPA1 (0.42) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL31310605 | 0.75 | TRPA1 (0.48) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL9147737 | 0.75 | TRPA1 (0.42) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL2079047 | 0.75 | TRPA1 (0.42) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL7604923 | 0.75 | TRPA1 (0.48) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL8755390 | 0.73 | TRPA1 (0.41) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL3298394 | 0.73 | TRPA1 (0.41) | TRPA1ATMCYP2A6CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514034-B1 | Silane products from reaction of solid silicon monoxide with aromatic halides | DOW CORNING (US) | 1996-02-28 | — | — | EP | disclosed |
| EP-0514034-A1 | Silane products from reaction of solid silicon monoxide with aromatic halides | DOW CORNING CORPORATION (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5120520-A | In presence of metal or metal-contianing catalyst | DOW CORNING CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |