SCHEMBL4274288

SCHEMBL4274288

COCc1c[nH]c(COC)n1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.36
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 1/20 0.33
CACNA1H O95180 1/20 0.32
HCAR2 Q8TDS4 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4912367 0.86 PKM (0.30) PKMKDM4E
SCHEMBL4908935 0.86 GCGR (0.31) PKMPOLB
SCHEMBL15555886 0.78
SCHEMBL19046336 0.78
SCHEMBL9036956 0.77
SCHEMBL18574023 0.77
SCHEMBL4270861 0.75 P2RX7 (0.32)
SCHEMBL4900302 0.72 HCAR2 (0.33) ALDH1A1HCAR2SMN1; SMN2
SCHEMBL4908857 0.71 L3MBTL1 (0.41) KDM4ETDP1HSD17B10CACNA1H
SCHEMBL29388840 0.71 HCAR2 (0.38) ALDH1A1HSD17B10POLBHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed