Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EIF4A1 | P60842 | 8/20 | 0.46 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883958 | 0.90 | CA12 (0.57) | CA12CA9ALDH1A1MAPTMAPK1 | |
| SCHEMBL811950 | 0.89 | CA12 (0.47) | CA12CA9ALDH1A1MAPTMAPK1 | |
| SCHEMBL4892128 | 0.89 | CA12 (0.47) | CA12CA9ALDH1A1MAPTMAPK1 | |
| SCHEMBL4891172 | 0.89 | EYA3 (0.57) | MAPK1TDP1EYA3PTPN1TTR | |
| SCHEMBL29464057 | 0.85 | EYA3 (0.65) | CA12CA9MAPK1TDP1EYA3 | |
| SCHEMBL4891187 | 0.85 | CA12 (0.44) | CA12CA9ALDH1A1MAPTMAPK1 | |
| SCHEMBL282873 | 0.85 | EYA3 (0.65) | CA12CA9MAPK1TDP1EYA3 | |
| SCHEMBL15362406 | 0.85 | EYA3 (0.53) | ALDH1A1MAPTMAPK1TDP1EYA3 | |
| SCHEMBL446008 | 0.84 | EYA3 (0.52) | MAPK1TDP1EYA3PTPN1TTR | |
| SCHEMBL12964086 | 0.84 | EYA3 (0.52) | MAPK1TDP1EYA3PTPN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120097944-A | Preparation of dronedarone Process for preparing intermediates | 山东新时代药业有限公司 | 2025-06-06 | — | — | CN | disclosed |
| US-9512097-B2 | Process for the preparation of 3-aroyl-5-aminobenzofuran derivatives | LEK PHARMACEUTICALS D.D. (SI) | 2016-12-06 | — | — | US | disclosed |
| US-9512097-B2 | Process for the preparation of 3-aroyl-5-aminobenzofuran derivatives | LEK PHARMACEUTICALS D.D. (SI) | 2016-12-06 | — | — | US | disclosed |
| EP-1699772-B1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | CLARIANT SPECIALTY FINE CHEM F (FR) | 2013-02-20 | — | — | EP | disclosed |
| EP-2508517-A1 | Process for the preparation of N-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | Clariant Specialty Fine Chemicals (France) (FR) | 2012-10-10 | — | — | EP | disclosed |
| US-7544817-B2 | Process for the preparation of n-alkyl-2(hydroxy-4benzoyl)-3 benzofurans and intermediates thereof | CLARIANT (FRANCE) (FR) | 2009-06-09 | — | — | US | disclosed |
| US-20070155831-A1 | Process for the preparation of n-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | WEYLCHEM LAMOTTE S.A.S. (FR) | 2007-07-05 | — | — | US | disclosed |
| EP-1699772-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | Clariant (France) S.A. (FR) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005066149-A1 | PROCESS FOR THE PREPERATION OF N-ALKYL-2(HYDROXY-4 BENZOYL)-3 BENZOFURANS AND ITS INTERMEDIATES THEREOF | CLARIANT (FRANCE) (FR) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155831-A1 | Process for the preparation of n-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof | CYP2F1, CYP2E1, CYP1B1 | CA12 4189/4885CA9 3924/4885ALDH1A1 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.