Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29464057 | 0.90 | EYA3 (0.65) | EYA3PTPN1HTTLMNAMAPK1 | |
| SCHEMBL15362406 | 0.90 | EYA3 (0.53) | EYA3PTPN1HTTLMNAMAPK1 | |
| SCHEMBL282873 | 0.90 | EYA3 (0.65) | EYA3PTPN1HTTLMNAMAPK1 | |
| SCHEMBL12964086 | 0.89 | EYA3 (0.52) | EYA3PTPN1HTTLMNAMAPK1 | |
| SCHEMBL15121433 | 0.89 | ESR1 (0.48) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL4891172 | 0.89 | EYA3 (0.57) | EYA3PTPN1HTTLMNAMAPK1 | |
| SCHEMBL4567254 | 0.88 | KDM5A (0.58) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL283212 | 0.88 | MAPK1 (0.60) | EYA3PTPN1HTTMAPK1TDP1 | |
| SCHEMBL12643780 | 0.87 | MAPK1 (0.51) | EYA3PTPN1HTTMAPK1TDP1 | |
| SCHEMBL30140853 | 0.87 | MAPK1 (0.51) | EYA3PTPN1HTTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674121-B2 | Process for the production of benzofurans | SANOFI (FR) | 2014-03-18 | — | — | US | disclosed |
| EP-2435398-B1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI SA (FR) | 2014-01-22 | — | — | EP | disclosed |
| US-20120065411-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI (FR) | 2012-03-15 | — | — | US | disclosed |
| WO-2010136500-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI-AVENTIS (FR) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065411-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | CYP2F1, CYP2B6, CYP4F2 | EYA3 4620/4885PTPN1 4492/4885HTT 2267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.