SCHEMBL5075835

SCHEMBL5075835

CC1(C)CC(C(c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)(C2CC(C)(C)NC(C)(C)C2)C(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)(C(=O)O)C(=O)O)CC(C)(C)N1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.39
KMT2A Q03164 6/20 0.39
MEN1 O00255 4/20 0.39
MAPT P10636 4/20 0.39
TSHR P16473 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 2/20 0.39
BLM P54132 2/20 0.39
ATM Q13315 2/20 0.39
HIF1A Q16665 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
USP2 O75604 1/20 0.39
CYP2D6 P10635 1/20 0.39
LMNA P02545 2/20 0.37
ALOX15 P16050 2/20 0.37
GMNN O75496 1/20 0.37
GABBR2 O75899 1/20 0.37
TP53 P04637 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7795980 0.83 ALDH1A1 (0.37) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL6025501 0.81 ALDH1A1 (0.37) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL10904372 0.78 MAOB (0.33) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL11174333 0.76 GAA (0.42) KMT2ATSHRCYP1A2CYP3A4HIF1A
SCHEMBL20428970 0.71 ALDH1A1 (0.41) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL5075832 0.71 ALDH1A1 (0.41) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL689100 0.71 NR5A2 (0.38) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL7795986 0.71 ALDH1A1 (0.36) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL4274838 0.70 MEN1 (0.32) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL9813579 0.70 KMT2A (0.48) ALDH1A1KMT2AMEN1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003809-B1 COPOLYETHERESTER COMPOSITIONS STABILIZED AGAINST OXIDATIVE DEGRADATION AND PROCESS FOR THEIR MANUFACTURE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-04-13 EP claimed
US-4185003-A PHENOLIC ANTIOXIDANT, HINDERED TETRAMETHYLPIPERIDINE ESTER PHOTOSTABILIZER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-01-22 US claimed
EP-0003809-A1 Copolyetherester compositions stabilized against oxidative degradation and process for their manufacture E.I. DU PONT DE NEMOURS AND COMPANY (US) 1979-09-05 EP claimed
EP-1856203-B1 THERMOPLASTIC POLYETHERESTER ELASTOMER COMPOSITION HAVING EXCELLENT FLEX ELASTICITY AND COVER FOR AIR-BAG DEVICE THEREBY KOLON PLASTICS INC (KR) 2015-11-11 EP disclosed
EP-1856203-A4 THERMOPLASTIC POLYETHERESTER ELASTOMER COMPOSITION HAVING EXCELLENT FLEX ELASTICITY AND COVER FOR AIR-BAG DEVICE THEREBY KOLON INC (KR) 2008-12-31 EP disclosed
US-20080249213-A1 Thermoplastic Polyetherester Elastomer Composition Having Excellent Flex Elasticity and Cover For Air-Bag Device Thereby KOLON INDUSTRIES, INC. (KR) 2008-10-09 US disclosed
EP-1856203-A1 THERMOPLASTIC POLYETHERESTER ELASTOMER COMPOSITION HAVING EXCELLENT FLEX ELASTICITY AND COVER FOR AIR-BAG DEVICE THEREBY KOLON INDUSTRIES, INC. (KR) 2007-11-21 EP disclosed
WO-2006095970-A1 THERMOPLASTIC POLYETHERESTER ELASTOMER COMPOSITION HAVING EXCELLENT FLEX ELASTICITY AND COVER FOR AIR-BAG DEVICE THEREBY KOLON INDUSTRIES, INC (KR) 2006-09-14 WO disclosed