SCHEMBL4275673

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8237608	0.87	SIGMAR1 (0.39)	TACR2SLC6A4SLC6A3SLC6A2KDM4E
	SCHEMBL4279734	0.82	TACR2 (0.60)	TACR2MEN1KMT2ACACNA2D1CACNA1B
	SCHEMBL4271169	0.82	TACR2 (0.43)	TACR2MEN1KMT2ACACNA2D1CACNA1B
	SCHEMBL4272230	0.81	TACR2 (0.42)	TACR2MEN1KMT2ACACNA2D1CACNA1B
	SCHEMBL5047955	0.75	CACNA1G (0.39)	TACR2KDM4EALDH1A1SIGMAR1HTR4
	SCHEMBL2794338	0.74	CACNA2D1 (0.50)	TACR2CACNA2D1CACNA1BCACNB1CACNA1C
	SCHEMBL2794421	0.71	CACNA2D1 (0.66)	CACNA2D1CACNA1BCACNB1CACNA1CSLC6A4
	SCHEMBL4275876	0.71	CACNA2D1 (0.73)	TACR2CACNA2D1CACNA1BCACNB1CACNA1C
	SCHEMBL4277158	0.69	CACNA2D1 (0.52)	MEN1KMT2ACACNA2D1CACNA1BCACNB1
	SCHEMBL2795615	0.69	CACNA2D1 (0.54)	CACNA2D1CACNA1BCACNB1CACNA1CSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.