Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266924 | 0.87 | CYP4A11 (0.52) | CYP4F2CYP4A11MTNR1AMTNR1BPPARA | |
| SCHEMBL4275713 | 0.86 | CYP4F2 (0.66) | CYP4F2CYP4A11MTNR1AMTNR1B | |
| SCHEMBL3169286 | 0.76 | PTGDR2 (0.43) | CYP4F2CYP4A11PPARGPPARA | |
| SCHEMBL4281884 | 0.75 | CHRM2 (0.36) | CYP4F2CYP4A11MTNR1AMTNR1B | |
| SCHEMBL4268356 | 0.75 | KCNH2 (0.50) | CYP4F2CYP4A11MTNR1AMTNR1B | |
| SCHEMBL4282042 | 0.74 | MTNR1A (0.48) | MTNR1AMTNR1BTAAR1PPARGPPARA | |
| SCHEMBL4266928 | 0.72 | CYP4A11 (0.72) | CYP4F2CYP4A11 | |
| SCHEMBL4275384 | 0.72 | PTGDR2 (0.55) | LMNA | |
| SCHEMBL4279632 | 0.70 | MTNR1A (0.47) | CYP4F2CYP4A11MTNR1AMTNR1BTAAR1 | |
| SCHEMBL7496943 | 0.69 | DAO (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |