Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3410024 | 0.94 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTLIN28ATDP1HDAC3 | |
| SCHEMBL2471917 | 0.94 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTLIN28ATDP1HDAC3 | |
| SCHEMBL19877250 | 0.91 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPTLIN28ATDP1HDAC3 | |
| SCHEMBL13661304 | 0.82 | HTT (0.54) | SMN1; SMN2MAPTLIN28ATDP1HDAC3 | |
| SCHEMBL5062633 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTLIN28ATDP1HDAC3 | |
| SCHEMBL2843465 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2TDP1ALOX15NPC1RAB9A | |
| SCHEMBL1065199 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTLIN28ATDP1HDAC3 | |
| SCHEMBL26521138 | 0.80 | SMN1; SMN2 (0.72) | SMN1; SMN2MAPTLIN28ATDP1HDAC3 | |
| SCHEMBL12762776 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPTLIN28ATDP1HDAC3 | |
| SCHEMBL7107996 | 0.79 | MAPT (0.84) | SMN1; SMN2MAPTLIN28ATDP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |