Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.56 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.56 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KDM5C | P41229 | 3/20 | 0.48 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.48 |
| ▸ | KDM6B | O15054 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28180482 | 1.00 | ACE (0.57) | ACEEGLN1LMNAALKBH5SUCNR1 | |
| SCHEMBL25203 | 0.87 | LMNA (0.75) | ACEEGLN1LMNAALKBH5SUCNR1 | |
| SCHEMBL1603817 | 0.87 | LMNA (0.75) | ACEEGLN1LMNAALKBH5SUCNR1 | |
| SCHEMBL22464687 | 0.87 | LMNA (0.75) | ACEEGLN1LMNAALKBH5SUCNR1 | |
| SCHEMBL30203931 | 0.87 | LMNA (0.75) | ACEEGLN1LMNAALKBH5SUCNR1 | |
| SCHEMBL4202343 | 0.87 | ACE (0.38) | ACEEGLN1LMNAALKBH5SUCNR1 | |
| SCHEMBL562396 | 0.87 | LMNA (0.75) | ACEEGLN1LMNAALKBH5SUCNR1 | |
| SCHEMBL483277 | 0.83 | — | — | |
| SCHEMBL27729446 | 0.82 | GPR84 (0.62) | ACELMNACAMK2AGPR84FFAR1 | |
| SCHEMBL15697547 | 0.80 | GPR84 (0.67) | ACEEGLN1LMNAALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12104160-B2 | Production of 4,6-dihydroxy-2-oxo-hexanoic acid | ZYMOCHEM, INC. (US) | 2024-10-01 | — | — | US | disclosed |
| CN-117486710-A | Photocatalytic synthesis method of succinic acid compounds | 北京大学 | 2024-02-02 | — | — | CN | disclosed |
| US-20220389433-A1 | HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES | ZYMOCHEM, INC. | 2022-12-08 | — | — | US | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| US-20200255840-A1 | HIGH YIELD ROUTE FOR THE PRODUCTION OF 1, 6-HEXANEDIOL | ZYMOCHEM INC (US) | 2020-08-13 | — | — | US | disclosed |
| US-9994881-B2 | Functionalized carboxylic acids and alcohols by reverse fatty acid oxidation in engineered microbes | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-06-12 | — | — | US | disclosed |
| EP-2753689-B1 | FUNCTIONALIZED CARBOXYLIC ACIDS AND ALCOHOLS BY REVERSE FATTY ACID OXIDATION | UNIV RICE WILLIAM M (US) | 2018-02-14 | — | — | EP | disclosed |
| US-20170044551-A1 | HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES | ZYMOCHEM INC. | 2017-02-16 | — | — | US | disclosed |
| US-20160237208-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | UNIV VANDERBILT (US) | 2016-08-18 | — | — | US | disclosed |
| EP-3047030-A2 | A HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES | Zymochem Inc. (US) | 2016-07-27 | — | — | EP | disclosed |
| CN-105745327-A | High-yield route for producing compounds from renewable resources | 兹莫克姆有限公司 | 2016-07-06 | — | — | CN | disclosed |
| WO-2015042201-A2 | A HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES | ZYMOCHEM INC. (US) | 2015-03-26 | — | — | WO | disclosed |
| US-20140273110-A1 | FUNCTIONALIZED CARBOXYLIC ACIDS AND ALCOHOLS BY REVERSE FATTY ACID OXIDATION | WILLIAM MARSH RICE UNIVERSITY (US) | 2014-09-18 | — | — | US | disclosed |
| US-20130142733-A1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | VANDERBILT UNIVERSITY (US) | 2013-06-06 | — | — | US | disclosed |
| US-8173764-B2 | Solubilization and targeted delivery of drugs with self-assembling amphiphilic polymers | ALLEXCEL INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-20100260743-A1 | Solubilization and Targeted Delivery of Drugs With Self-Assembling Amphiphilic Polymers | ALLEXCEL, INC. (US) | 2010-10-14 | — | — | US | disclosed |
| US-20100239659-A1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTI-CANCER AGENTS | ALLEXCEL., INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-7511160-B2 | Lactone derivative and its manufacturing method | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2009-03-31 | — | — | US | disclosed |
| US-7511160-B2 | Lactone derivative and its manufacturing method | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2009-03-31 | — | — | US | disclosed |
| US-4902512-A | Rhamnolipid liposomes | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY AND SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1990-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239659-A1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTI-CANCER AGENTS | CD44, EPCAM, EGFR | ACE 4006/4885EGLN1 4706/4885LMNA 2786/4885 |
| US-20130142733-A1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | DSTN, PARN, CTSA | ACE 648/4885EGLN1 623/4885LMNA 1043/4885 |
| US-20100260743-A1 | Solubilization and Targeted Delivery of Drugs With Self-Assembling Amphiphilic Polymers | CD44, ABCG2, ABCC1 | ACE 2022/4885EGLN1 4649/4885LMNA 1169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.