Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PCNA | P12004 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4273195 | 0.88 | FFAR1 (0.54) | THRATHRBPPARGRXRAPGR | |
| SCHEMBL4271148 | 0.86 | THRA (0.57) | THRATHRBPGRARPOLB | |
| SCHEMBL4273581 | 0.86 | THRA (0.57) | THRATHRBPPARGRXRAPGR | |
| SCHEMBL4265967 | 0.84 | F2 (0.49) | RXRASMN1; SMN2IDO1F2RXRB | |
| SCHEMBL4274308 | 0.84 | RXRA (0.50) | THRATHRBPPARGRXRAPGR | |
| SCHEMBL6243823 | 0.81 | FFAR1 (0.53) | RXRASLC26A3FFAR1RXRB | |
| SCHEMBL1052818 | 0.79 | AKR1B1 (0.58) | LMNACYP1A2POLBHPGDSMN1; SMN2 | |
| SCHEMBL6723744 | 0.79 | THRA (0.43) | THRATHRBPGRARPCNA | |
| SCHEMBL6721162 | 0.78 | F2 (0.46) | THRATHRBPGRABCB11LMNA | |
| SCHEMBL6725044 | 0.78 | F2 (0.46) | LMNAHPGDSMN1; SMN2SLC26A3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066362-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | Boston Scientific Limited (BB) | 2009-06-10 | — | — | EP | claimed |
| WO-2008033198-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | BOSTON SCIENTIFIC LIMITED (BB) | 2008-03-20 | — | — | WO | claimed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | claimed |
| US-8507639-B2 | Polyamide block polymers containing iodoarylcarboxyl pendant groups and modified poly(meth)acrylamide; coupling; for tracking movement of a catheter through the body or inflation of balloon at site | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| EP-2066362-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | Boston Scientific Limited (BB) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008033198-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | BOSTON SCIENTIFIC LIMITED (BB) | 2008-03-20 | — | — | WO | disclosed |
| US-20080064848-A1 | Radiopaque amide polymers and medical devices formed thereof | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |