SCHEMBL4276663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4279613	0.90	PDE4B (0.48)	PDE4BPDE4APDE4CPDE4DMAPK1
	SCHEMBL4271328	0.89	PTGS2 (0.45)	PDE4BPDE4APDE4CPDE4DMEN1
	SCHEMBL20053165	0.89	PDE4A (0.44)	PDE4BPDE4APDE4CPDE4DMEN1
	SCHEMBL4271668	0.88	PDE4A (0.44)	PDE4BPDE4APDE4CPDE4DMEN1
	SCHEMBL4269941	0.88	PTGS2 (0.46)	PDE4BPDE4APDE4CPDE4DKMT2A
	SCHEMBL4280362	0.87	PDE4B (0.45)	PDE4BPDE4APDE4CPDE4DHPGD
	SCHEMBL4285834	0.87	PDE4B (0.43)	PDE4BPDE4APDE4CPDE4DHPGD
	SCHEMBL4639291	0.86	PDE4B (0.47)	PDE4BPDE4APDE4CPDE4DMAPK1
	SCHEMBL4279381	0.86	KMT2A (0.43)	PDE4BPDE4APDE4CPDE4DMEN1
	SCHEMBL4278639	0.86	PDE4B (0.48)	PDE4BPDE4APDE4CPDE4DMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.