SCHEMBL4276906

SCHEMBL4276906

CCCCCCOc1ccc(C(=O)O)cn1

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.69
TP53 P04637 1/20 0.62
TSHR P16473 1/20 0.62
PLA2G4B P0C869 5/20 0.60
RARB P10826 3/20 0.57
L3MBTL1 Q9Y468 1/20 0.55
PLA2G4A P47712 1/20 0.55
HCAR3 P49019 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6946501 1.00 MAPT (0.69) MAPTTP53TSHRPLA2G4BRARB
SCHEMBL9578575 1.00 MAPT (0.69) MAPTTP53TSHRPLA2G4BRARB
SCHEMBL7548158 1.00 MAPT (0.69) MAPTTP53TSHRPLA2G4BRARB
SCHEMBL14125959 1.00 MAPT (0.69) MAPTTP53TSHRPLA2G4BRARB
SCHEMBL10662876 0.98 MAPT (0.71) MAPTTP53TSHRPLA2G4BRARB
SCHEMBL1461142 0.94 MAPT (0.73) MAPTTP53TSHRPLA2G4BRARB
SCHEMBL10657063 0.89 MAPT (0.75) MAPTTP53TSHRL3MBTL1HCAR3
SCHEMBL7555804 0.86 MAPT (0.50) MAPTTP53TSHRPLA2G4BRARB
SCHEMBL6953681 0.86 NNMT (0.59) MAPTTP53TSHRPLA2G4B
SCHEMBL7219864 0.85 LMNA (0.62) MAPTTSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2123639-B1 PROCESS FOR PRODUCTION OF 2,3'-BIPYRIDYL-6'-ONE FUJIFILM FINECHEMICALS CO LTD (JP) 2014-03-26 EP disclosed
EP-2123639-A1 PROCESS FOR PRODUCTION OF 2,3'-BIPYRIDYL-6'-ONE Fujifilm Finechemicals Co. Ltd. (JP) 2009-11-25 EP disclosed
US-6624309-B1 Administering 4-heterocyclicbenzamide derivative BRISTOL-MYERS SQUIBB COMPANY 2003-09-23 US disclosed
US-20020137968-A1 Benzoic acid derivatives and related compounds as antiarrhythmic agents LLOYD JOHN (US) 2002-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020137968-A1 Benzoic acid derivatives and related compounds as antiarrhythmic agents SCN1A, SCN1B, NR0B1 MAPT 4755/4885TP53 4875/4885TSHR 2565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.