Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.60 |
| ▸ | RARB | P10826 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9578575 | 1.00 | MAPT (0.69) | MAPTTP53TSHRPLA2G4BRARB | |
| SCHEMBL7548158 | 1.00 | MAPT (0.69) | MAPTTP53TSHRPLA2G4BRARB | |
| SCHEMBL4276906 | 1.00 | MAPT (0.69) | MAPTTP53TSHRPLA2G4BRARB | |
| SCHEMBL14125959 | 1.00 | MAPT (0.69) | MAPTTP53TSHRPLA2G4BRARB | |
| SCHEMBL10662876 | 0.98 | MAPT (0.71) | MAPTTP53TSHRPLA2G4BRARB | |
| SCHEMBL1461142 | 0.94 | MAPT (0.73) | MAPTTP53TSHRPLA2G4BRARB | |
| SCHEMBL10657063 | 0.89 | MAPT (0.75) | MAPTTP53TSHRL3MBTL1HCAR3 | |
| SCHEMBL7555804 | 0.86 | MAPT (0.50) | MAPTTP53TSHRPLA2G4BRARB | |
| SCHEMBL6953681 | 0.86 | NNMT (0.59) | MAPTTP53TSHRPLA2G4B | |
| SCHEMBL7219864 | 0.85 | LMNA (0.62) | MAPTTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639189-B1 | PYRIDYLPYRIMIDINES, A METHOD OF PREPARING THEM, AND THEIR USE IN LIQUID-CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2003-02-19 | — | — | EP | disclosed |
| EP-0639189-A1 | PYRIDYLPYRIMIDINES, A METHOD OF PREPARING THEM, AND THEIR USE IN LIQUID-CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-22 | — | — | EP | disclosed |
| EP-0639189-A4 | PYRIDYLPYRIMIDINES, A METHOD OF PREPARING THEM, AND THEIR USE IN LIQUID-CRYSTAL MIXTURES. | AVENTIS RES & TECH GMBH & CO (DE) | 1993-09-17 | — | — | EP | disclosed |
| US-5164113-A | Ferroelectric, polarization promoters | MITSUBISHI RAYON CO., LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| WO-1992012974-A1 | PYRIDYLPYRIMIDINES, A METHOD OF PREPARING THEM, AND THEIR USE IN LIQUID-CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-06 | — | — | WO | disclosed |
| EP-0396410-A2 | Optical active compound and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-11-07 | — | — | EP | disclosed |