SCHEMBL42772

SCHEMBL42772

CC(C)(C)N(C(N)=O)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
ALOX15 P16050 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
TSHR P16473 2/20 0.32
CYP1A2 P05177 1/20 0.32
NFKB1 P19838 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
THPO P40225 1/20 0.32
ALDH1A1 P00352 2/20 0.31
OR51E2 Q9H255 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5702809 0.75 TDP1 (0.32) LMNAALOX15BLMPMP22TDP1
Carbamic Acid SCHEMBL3591976 0.75 ACHE (0.41) LMNAALOX15BLMPMP22TSHR
SCHEMBL19473677 0.72 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL29271959 0.72 SOAT1 (0.36) LMNACYP1A2ALDH1A1
SCHEMBL15345846 0.71 KDM4E (0.36)
SCHEMBL19512282 0.71
SCHEMBL3926619 0.71 LMNA (0.31) LMNAALOX15
SCHEMBL17341040 0.71
SCHEMBL965805 0.71
SCHEMBL25424742 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219544-A Preparation method of N-tert-butyl-3-aminoindole derivatives and N-tert-butyl-3-aminoindole derivatives 常州大学 2024-12-31 CN claimed
CN-117865874-A N-tertiary butyl-3-amino-4, 5,6, 7-tetrahydroindole derivative and preparation method thereof 常州大学 2024-04-12 CN claimed
CN-117820139-A Preparation method of 2-tertiary butyl amino benzaldehyde derivative 常州大学 2024-04-05 CN claimed
CN-117327010-A Preparation method of 3-tertiary butyl amino acrylamide derivative 常州大学 2024-01-02 CN claimed
CN-113683551-B N-tert-butyl-2-phenylindole derivative, preparation method and application 常州大学 2023-09-26 CN claimed
CN-113121542-B 5, 10-indolino [3,2-b ] indole derivative and synthetic method and application thereof 常州大学 2022-09-30 CN claimed
CN-113683551-A N-tert-butyl-2-phenylindole derivative, preparation method and application 常州大学 2021-11-23 CN claimed
CN-113121542-A 5, 10-indolino [3,2-b ] indole derivative and synthesis method and application thereof 常州大学 2021-07-16 CN claimed
CN-117820139-B Preparation method of 2-tertiary butyl amino benzaldehyde derivative 常州大学 2026-02-27 CN disclosed
CN-115819338-B Preparation method of o-tertiary butyl amino benzamide derivative 常州大学 2025-04-25 CN disclosed
CN-119219544-A Preparation method of N-tert-butyl-3-aminoindole derivatives and N-tert-butyl-3-aminoindole derivatives 常州大学 2024-12-31 CN disclosed
CN-119219544-A Preparation method of N-tert-butyl-3-aminoindole derivatives and N-tert-butyl-3-aminoindole derivatives 常州大学 2024-12-31 CN disclosed
CN-119192150-A 3-Aldehyde indole derivative and preparation method thereof 常州大学 2024-12-27 CN disclosed
CN-117865874-A N-tertiary butyl-3-amino-4, 5,6, 7-tetrahydroindole derivative and preparation method thereof 常州大学 2024-04-12 CN disclosed
EP-0672038-A1 HERBICIDES ZENECA LIMITED (GB) 1995-09-20 EP disclosed
WO-1995000112-A1 PHOTOPROTECTION COMPOSITIONS COMPRISING CERTAIN CHELATING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1995-01-05 WO disclosed
CN-1095066-A Weedicide ZENECA LTD (GB) 1994-11-16 CN disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed
EP-0554400-A1 RETROVIRAL PROTEASE INHIBITORS. MONSANTO CO (US) 1993-08-11 EP disclosed
WO-1992008698-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed