Sulfuric Acid

Sulfuric Acid

SCHEMBL4277384

Cc1cn(C)cn1.O=S(=O)(O)O

nearest known ligand 0.42

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.38
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 3/20 0.36
LMNA P02545 2/20 0.36
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
TSHR P16473 2/20 0.35
MTOR P42345 1/20 0.35
HRH4 Q9H3N8 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
MEN1 O00255 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
CYP2E1 P05181 1/20 0.34
CYP2A6 P11509 1/20 0.34
CYP2B6 P20813 1/20 0.34
TP53 P04637 1/20 0.34
MAPK10 P53779 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL22027392 0.84
SCHEMBL304175 0.74 LMNA (0.46) GAAALDH1A1KMT2ALMNATSHR
Hydrochloric Acid SCHEMBL27398725 0.72 LMNA (0.45) GAAALDH1A1KMT2ALMNATSHR
SCHEMBL25202996 0.69 LPO (0.38) ALDH1A1KMT2ACYP2C9CYP2C19TSHR
SCHEMBL27387038 0.67
Sulfuric Acid SCHEMBL4277252 0.67 GAA (0.30) GAA
SCHEMBL733288 0.67 LMNA (0.47) GAAALDH1A1KMT2ALMNATSHR
SCHEMBL4200114 0.65 TSHR (0.46) GAAALDH1A1KMT2ALMNATSHR
SCHEMBL4616133 0.65 KMT2A (0.49) GAAALDH1A1KMT2ALMNATSHR
SCHEMBL50543 0.65 LMNA (0.46) GAAALDH1A1KMT2ALMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615644-B2 catalytic producing methanol from methane gas, by bubbling methane through the oxidation catalyst liquid mixture containing an imidazolium ionic liquid catalyst and a dissolved platinum compound as PtCl2, PtCl4, PtO2; cost efficiency, energy efficiency, low pollution, environmentally friendly CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2009-11-10 US disclosed
US-20060069169-A1 Use of ionic liquids as coordination ligands for organometallic catalysts CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-03-30 US disclosed