SCHEMBL4278064

SCHEMBL4278064

Cc1[c]ccc(C)c1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NOTUM Q6P988 2/20 0.38
CYP3A4 P08684 3/20 0.36
ACHE P22303 1/20 0.36
ALDH1A1 P00352 4/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MAPK1 P28482 1/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
LDHA P00338 1/20 0.33
LDHB P07195 1/20 0.33
KDM4E B2RXH2 3/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7771345 0.81 KMT2A (0.39) TDP1NOTUMCYP3A4ALDH1A1KDM4E
SCHEMBL8641020 0.81 TDP1 (0.38) TDP1L3MBTL1NOTUMCYP3A4ACHE
SCHEMBL3733647 0.79 KDM4E (0.38) TDP1L3MBTL1NOTUMCYP3A4ACHE
SCHEMBL3392120 0.73 TDP1 (0.48) TDP1L3MBTL1NOTUMCYP3A4ACHE
SCHEMBL16223153 0.70 MEN1 (0.39) TDP1NOTUMCYP3A4ALDH1A1SMN1; SMN2
SCHEMBL4278063 0.70 MCL1 (0.35) TDP1NOTUMCYP3A4ALDH1A1SMN1; SMN2
SCHEMBL355272 0.69 TDP1 (0.61) TDP1L3MBTL1NOTUMCYP3A4ALDH1A1
SCHEMBL6907913 0.67 TDP1 (0.59) TDP1L3MBTL1NOTUMCYP3A4ALDH1A1
Hydrochloric Acid SCHEMBL6113042 0.67 TDP1 (0.59) TDP1L3MBTL1NOTUMCYP3A4ALDH1A1
SCHEMBL6916435 0.67 TDP1 (0.59) TDP1L3MBTL1NOTUMCYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10251392-B2 Antimicrobial devices and compositions AVENT, INC. (US) 2019-04-09 US disclosed
US-20090035342-A1 Antimicrobial Devices and Compositions AVANOS MEDICAL SALES, LLC 2009-02-05 US disclosed
EP-1781098-A2 ANTIMICROBIAL DEVICES AND COMPOSITIONS ACRYMED, INC. (US) 2007-05-09 EP disclosed
WO-2006015317-A2 ANTIMICROBIAL DEVICES AND COMPOSITIONS ACRYMED, INC. (US) 2006-02-09 WO disclosed
US-4551350-A AMINO PLAST SWS SILICONES CORPORATION (US) 1985-11-05 US disclosed
US-4520176-A DILUENT, DURABLE PRESS RESIN CONTAINING AN AMINOPLAST AND AN ALOEHYDE SWS SILICONES CORPORATION (US) 1985-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10251392-B2 Antimicrobial devices and compositions AAAS, AOC1, COL14A1 TDP1 4268/4885L3MBTL1 4200/4885NOTUM 3071/4885
US-20090035342-A1 Antimicrobial Devices and Compositions AAAS, AOC1, COL14A1 TDP1 4268/4885L3MBTL1 4200/4885NOTUM 3071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.