SCHEMBL4278300

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4282706	1.00	CACNA1I (0.59)	CACNA1IKCNH2CCR2HTR7CACNA1H
	SCHEMBL4278302	1.00	CACNA1I (0.59)	CACNA1IKCNH2CCR2HTR7CACNA1H
	SCHEMBL4279453	0.90	HTR7 (0.50)	CACNA1IKCNH2CCR2HTR7CACNA1H
	SCHEMBL4279456	0.90	HTR7 (0.50)	CACNA1IKCNH2CCR2HTR7CACNA1H
	SCHEMBL4273405	0.89	KMT2A (0.56)	CACNA1IKCNH2CCR2HDAC6HDAC3
	SCHEMBL4273401	0.89	KMT2A (0.56)	CACNA1IKCNH2CCR2HDAC6HDAC3
	SCHEMBL8371834	0.89	HDAC6 (0.47)	CACNA1IKCNH2CCR2HTR7CACNA1H
	SCHEMBL4280620	0.89	CCR2 (0.54)	CACNA1IKCNH2CCR2HDAC6HDAC3
	SCHEMBL8371286	0.89	HDAC6 (0.46)	CACNA1IKCNH2CCR2HTR7CACNA1H
	SCHEMBL4280616	0.89	CCR2 (0.54)	CACNA1IKCNH2CCR2HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.