SCHEMBL4280487

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4280559	0.88	HPGD (0.40)	NPC1RAB9ACHRM4KCNH2CACNA1I
	SCHEMBL19113070	0.82	HRH3 (0.50)	NPC1RAB9AHRH3CHRM4HTT
	SCHEMBL4271286	0.82	CHRM4 (0.45)	NPC1RAB9ACHRM4KCNH2CACNA1I
	SCHEMBL4269225	0.80	KCNH2 (0.46)	NPC1RAB9AHRH3KCNH2CACNA1I
	SCHEMBL10133116	0.77	RAB9A (0.77)	NPC1RAB9AHRH3HTTMAPK14
	SCHEMBL4278333	0.76	RAB9A (0.45)	NPC1RAB9ACHRM4KCNH2CACNA1I
	SCHEMBL4272846	0.75	MEN1 (0.53)	RAB9AKCNH2CACNA1ILMNAMEN1
	SCHEMBL8374007	0.73	KCNH2 (0.44)	NPC1RAB9AKCNH2CACNA1IHTT
	SCHEMBL4277690	0.72	KCNH2 (0.48)	KCNH2CACNA1IKMT2AALDH1A1
	SCHEMBL4280615	0.72	KCNH2 (0.45)	NPC1KCNH2CACNA1IMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.