SCHEMBL4280558

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4278753	0.90	CACNA1I (0.72)	CACNA1IKCNH2HTR7CACNA1HCYP2D6
	SCHEMBL4279218	0.90	CACNA1I (0.67)	CACNA1IKCNH2CACNA1HCYP2D6
	SCHEMBL4277744	0.89	KMT2A (0.55)	CACNA1IKCNH2HTR7CACNA1HCYP2D6
	SCHEMBL4274989	0.89	CCR2 (0.56)	CACNA1IKCNH2CCR2POLBHDAC3
	SCHEMBL15353985	0.88	HDAC6 (0.50)	CACNA1IKCNH2HTR7CCR2HDAC3
	SCHEMBL14770045	0.87	KCNH2 (0.70)	CACNA1IKCNH2HTR7CACNA1HCYP2D6
	SCHEMBL4272222	0.86	CACNA1I (0.60)	CACNA1IKCNH2CACNA1HCYP2D6
	SCHEMBL4278285	0.86	CACNA1I (0.66)	CACNA1IKCNH2HTR7CACNA1HCYP2D6
	SCHEMBL4274696	0.86	KCNH2 (0.48)	CACNA1IKCNH2HTR7LMNASMN1; SMN2
	SCHEMBL4275111	0.86	CACNA1I (0.59)	CACNA1IKCNH2CACNA1HCYP2D6CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.