SCHEMBL4272471

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4281082	0.92	MAPT (0.43)	NPC1RAB9AMEN1KMT2AL3MBTL1
	SCHEMBL4280683	0.92	CTNNB1 (0.43)	NPC1RAB9AKMT2AL3MBTL1MAPT
	SCHEMBL13701429	0.92	PTGS2 (0.48)	NPC1RAB9AMEN1KMT2APTGS2
	SCHEMBL4277709	0.87	SMN1; SMN2 (0.43)	NPC1RAB9AMEN1KMT2AL3MBTL1
	SCHEMBL4271880	0.87	TSHR (0.41)	NPC1RAB9AMEN1KMT2AMAPT
	SCHEMBL4278360	0.87	PTGS2 (0.44)	NPC1RAB9AMEN1KMT2APTGS2
	SCHEMBL4270475	0.87	IDO1 (0.41)	NPC1RAB9AMEN1KMT2ATP53
	SCHEMBL4280738	0.87	CTNNB1 (0.39)	NPC1RAB9AMEN1KMT2ATP53
	SCHEMBL29813417	0.87	CTNNB1 (0.39)	NPC1RAB9AMEN1KMT2ATP53
	SCHEMBL4280709	0.86	LCLAT1 (0.39)	NPC1RAB9AL3MBTL1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.