SCHEMBL4280964

SCHEMBL4280964

CCCOc1ccc(C(=O)c2c(O)cc(C)cc2F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 1/20 0.47
SLC5A2 P31639 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
PLK1 P53350 1/20 0.47
ABCG2 Q9UNQ0 1/20 0.45
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.43
ELANE P08246 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
CYP1A1 P04798 1/20 0.42
CYP1B1 Q16678 1/20 0.42
CYP1A2 P05177 2/20 0.41
NPC1 O15118 1/20 0.41
CYP2C9 P11712 1/20 0.41
RAB9A P51151 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP2C19 P33261 1/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4292209 0.89 MAPT (0.51) SLC5A1SLC5A2L3MBTL1PLK1MAPT
SCHEMBL4287058 0.85 SLC5A1 (0.48) SLC5A1SLC5A2L3MBTL1PLK1ABCG2
SCHEMBL4286723 0.84 L3MBTL1 (0.44) L3MBTL1PLK1ABCG2MAPTTHRB
SCHEMBL4294582 0.84 SLC5A1 (0.47) SLC5A1SLC5A2L3MBTL1PLK1ABCG2
SCHEMBL4283203 0.82 MEN1 (0.47) MAPTNPC1RAB9AALDH1A1CYP2C19
SCHEMBL27746720 0.82 SLC5A1 (0.48) SLC5A1SLC5A2L3MBTL1PLK1ABCG2
SCHEMBL4284273 0.81 SLC5A1 (0.47) SLC5A1SLC5A2L3MBTL1PLK1ABCG2
SCHEMBL4280994 0.78 PARP10 (0.50) MAPTNPC1RAB9AALDH1A1LMNA
SCHEMBL28781281 0.77 SLC5A1 (0.43) SLC5A1SLC5A2L3MBTL1PLK1ABCG2
SCHEMBL6341040 0.76 L3MBTL1 (0.68) L3MBTL1PLK1MAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101472937-A Benzylphenylglucopyranoside Derivatives DAIICHI SANKYO CO LTD (JP) 2009-07-01 CN disclosed
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 SLC5A1 1/4885SLC5A2 2/4885L3MBTL1 2087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.