SCHEMBL4287058

SCHEMBL4287058

CCCOc1ccc(C(=O)c2c(O)cc(CO)cc2F)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 1/20 0.48
SLC5A2 P31639 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.45
PLK1 P53350 1/20 0.45
LTA4H P09960 1/20 0.42
CYP19A1 P11511 2/20 0.42
MAOB P27338 2/20 0.41
RARA P10276 1/20 0.41
RARB P10826 1/20 0.41
LMNA P02545 2/20 0.41
ABCG2 Q9UNQ0 1/20 0.41
MAOA P21397 1/20 0.40
PTPN7 P35236 2/20 0.40
DUSP3 P51452 2/20 0.40
NPC1 O15118 1/20 0.40
MAPT P10636 1/20 0.40
NFKB1 P19838 1/20 0.40
RAB9A P51151 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4279729 0.90 KDM4E (0.49) SLC5A1SLC5A2L3MBTL1PLK1MAOB
SCHEMBL4294582 0.89 SLC5A1 (0.47) SLC5A1SLC5A2L3MBTL1PLK1LTA4H
SCHEMBL27746720 0.87 SLC5A1 (0.48) SLC5A1SLC5A2L3MBTL1PLK1LTA4H
SCHEMBL4284273 0.86 SLC5A1 (0.47) SLC5A1SLC5A2L3MBTL1PLK1LTA4H
SCHEMBL4280964 0.85 SLC5A1 (0.47) SLC5A1SLC5A2L3MBTL1PLK1LTA4H
SCHEMBL4287006 0.84 NFKB1 (0.46) SLC5A1SLC5A2LMNANPC1MAPT
SCHEMBL4282675 0.81 PARP10 (0.47) MAOBNPC1RAB9ASMN1; SMN2
SCHEMBL27746671 0.80 SLC5A1 (0.47) SLC5A1SLC5A2L3MBTL1PLK1MAOB
SCHEMBL4279710 0.76 MAOB (0.48) SLC5A1SLC5A2L3MBTL1PLK1LTA4H
SCHEMBL4279712 0.74 KDM4E (0.49) SLC5A1SLC5A2L3MBTL1PLK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101472937-A Benzylphenylglucopyranoside Derivatives DAIICHI SANKYO CO LTD (JP) 2009-07-01 CN disclosed
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 SLC5A1 1/4885SLC5A2 2/4885L3MBTL1 2087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.