SCHEMBL4294582

SCHEMBL4294582

CCCOc1ccc(C(=O)c2c(O)cc(CBr)cc2F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 1/20 0.47
SLC5A2 P31639 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.44
PLK1 P53350 1/20 0.44
DPP4 P27487 2/20 0.43
CYP19A1 P11511 2/20 0.41
LTA4H P09960 1/20 0.41
MAPT P10636 2/20 0.41
MAOB P27338 2/20 0.40
RARA P10276 1/20 0.40
RARB P10826 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.40
LMNA P02545 1/20 0.40
MAOA P21397 1/20 0.40
NPC1 O15118 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27746720 0.91 SLC5A1 (0.48) SLC5A1SLC5A2L3MBTL1PLK1DPP4
SCHEMBL4287058 0.89 SLC5A1 (0.48) SLC5A1SLC5A2L3MBTL1PLK1CYP19A1
SCHEMBL4284273 0.85 SLC5A1 (0.47) SLC5A1SLC5A2L3MBTL1PLK1CYP19A1
SCHEMBL4280964 0.84 SLC5A1 (0.47) SLC5A1SLC5A2L3MBTL1PLK1CYP19A1
SCHEMBL4290549 0.81 PARP10 (0.46) MAOBNPC1RAB9ASMN1; SMN2
SCHEMBL4279729 0.79 KDM4E (0.49) SLC5A1SLC5A2L3MBTL1PLK1MAPT
SCHEMBL27746671 0.77 SLC5A1 (0.47) SLC5A1SLC5A2L3MBTL1PLK1MAPT
SCHEMBL4279710 0.75 MAOB (0.48) SLC5A1SLC5A2L3MBTL1PLK1LTA4H
SCHEMBL6341040 0.73 L3MBTL1 (0.68) L3MBTL1PLK1CYP19A1LTA4HMAPT
SCHEMBL4292209 0.73 MAPT (0.51) SLC5A1SLC5A2L3MBTL1PLK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 SLC5A1 1/4885SLC5A2 2/4885L3MBTL1 2087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.