Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | FABP1 | P07148 | 1/20 | 0.56 |
| ▸ | FABP6 | P51161 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.56 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyramidol SCHEMBL21963 | 0.84 | CYP2D6 (1.00) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Phenyramidol SCHEMBL29500950 | 0.84 | CYP2D6 (1.00) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| SCHEMBL3758388 | 0.84 | CYP2D6 (0.66) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Phenyramidol SCHEMBL13310219 | 0.84 | CYP2D6 (1.00) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Phenyramidol SCHEMBL13310227 | 0.84 | CYP2D6 (1.00) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Phenyramidol SCHEMBL121004 | 0.82 | CYP2D6 (0.97) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Phenyramidol SCHEMBL20769334 | 0.82 | CYP2D6 (0.97) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Phenyramidol SCHEMBL29375712 | 0.82 | CYP2D6 (0.97) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| SCHEMBL11166206 | 0.81 | CYP2D6 (0.58) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Hydrochloric Acid SCHEMBL10885224 | 0.80 | CYP2D6 (0.57) | CYP2D6FABP1FABP6FDPSCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615569-B2 | Inhibitors of ion channels | ICAGEN, INC. (US) | 2009-11-10 | — | — | US | disclosed |
| US-20070078145-A1 | INHIBITORS OF ION CHANNELS | ICAGEN (US) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078145-A1 | INHIBITORS OF ION CHANNELS | TRPV1, TRPA1, CACNA1B | CYP2D6 2049/4885FABP1 3931/4885FABP6 3722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.