Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | FABP1 | P07148 | 1/20 | 0.51 |
| ▸ | FABP6 | P51161 | 1/20 | 0.51 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281005 | 0.84 | CYP2D6 (0.72) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| SCHEMBL5575974 | 0.82 | GRIN2D (0.51) | CYP2D6GRIN2DGRIN3BGRIN1GRIN2A | |
| Phenyramidol SCHEMBL21963 | 0.79 | CYP2D6 (1.00) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Phenyramidol SCHEMBL13310227 | 0.79 | CYP2D6 (1.00) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Phenyramidol SCHEMBL13310219 | 0.79 | CYP2D6 (1.00) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Phenyramidol SCHEMBL29500950 | 0.79 | CYP2D6 (1.00) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| SCHEMBL1831588 | 0.79 | CYP2D6 (0.56) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| SCHEMBL14198659 | 0.79 | CYP2D6 (0.56) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Phenyramidol SCHEMBL29375712 | 0.78 | CYP2D6 (0.97) | CYP2D6FABP1FABP6FDPSCXCR4 | |
| Phenyramidol SCHEMBL20769334 | 0.78 | CYP2D6 (0.97) | CYP2D6FABP1FABP6FDPSCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2010-11-25 | — | — | US | disclosed |
| US-7790747-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090099205-A1 | Chemokine receptor binding compounds | GENZYME CORPORATION | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | CCR5, CXCR3, CCL5 | CYP2D6 3964/4885GRIN2D 3183/4885GRIN3B 607/4885 |
| US-20090099205-A1 | Chemokine receptor binding compounds | CCR5, CXCR3, CCL5 | CYP2D6 3964/4885GRIN2D 3183/4885GRIN3B 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.