Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 6/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643387 | 0.94 | HTR6 (0.56) | HTR2ARETHTR6IDO1 | |
| Hydrochloric Acid SCHEMBL27196405 | 0.93 | HTR6 (0.55) | HTR2ARETHTR6IDO1 | |
| SCHEMBL61507 | 0.86 | HTR6 (0.59) | HTR2ARETHTR6IDO1 | |
| SCHEMBL29681415 | 0.86 | HTR6 (0.59) | HTR2ARETHTR6IDO1 | |
| SCHEMBL62360 | 0.86 | HTR6 (0.59) | HTR2ARETHTR6IDO1 | |
| Oxalic Acid SCHEMBL5361082 | 0.85 | HTR6 (0.56) | HTR2ARETHTR6 | |
| Hydrochloric Acid SCHEMBL15818880 | 0.85 | HTR6 (0.57) | HTR2ARETHTR6IDO1 | |
| SCHEMBL18440732 | 0.81 | CYP19A1 (0.55) | HTR2ARETIDO1SIGMAR1 | |
| SCHEMBL15320085 | 0.81 | HTR6 (0.46) | HTR6IDO1SIGMAR1 | |
| SCHEMBL9014682 | 0.79 | SIGMAR1 (0.49) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835461-B2 | Substituted 3-hydroxy-4-pyridone derivative | SHIONOGI & CO., LTD. (JP) | 2014-09-16 | — | — | US | disclosed |
| EP-2412708-A1 | SUBSTITUTED 3-HYDROXY-4-PYRIDONE DERIVATIVE | Shionogi&Co., Ltd. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20120022255-A1 | SUBSTITUTED 3-HYDROXY-4-PYRIDONE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |
| WO-2010110231-A1 | SUBSTITUTED 3-HYDROXY-4-PYRIDONE DERIVATIVE | 塩野義製薬株式会社 (JP) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022255-A1 | SUBSTITUTED 3-HYDROXY-4-PYRIDONE DERIVATIVE | ENDOD1, CNBP, DPP4 | HTR2A 2604/4885RET 4627/4885HTR6 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.