Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10551218 | 0.95 | CYP19A1 (0.54) | SIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL5724904 | 0.87 | HTR6 (0.51) | CYP19A1TBXAS1BCHE | |
| SCHEMBL78964 | 0.85 | SIGMAR1 (0.54) | SIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL16034237 | 0.80 | CYP19A1 (0.49) | SIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL428148 | 0.79 | HTR2A (0.53) | SIGMAR1 | |
| SCHEMBL5477158 | 0.79 | CYP19A1 (0.55) | SIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL18440732 | 0.79 | CYP19A1 (0.55) | SIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL15320085 | 0.79 | HTR6 (0.46) | SIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL19358515 | 0.77 | BCHE (0.50) | SIGMAR1BCHE | |
| SCHEMBL6077542 | 0.77 | CYP19A1 (0.54) | SIGMAR1CYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5495022-A | Piperidines and piperazines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-02-27 | — | — | US | disclosed |
| EP-0634398-A1 | 4-Phenylpiperidinyl-1/-piperazinyl-1-ethylsubstituted benzofusedheterocycles as antiarrhythmic agents | MERCK PATENT GmbH (DE) | 1995-01-18 | — | — | EP | disclosed |