SCHEMBL4281481

SCHEMBL4281481

O=C(O)CCCC(S)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.73
RNPEP Q9H4A4 2/20 0.58
ENPEP Q07075 3/20 0.50
GSTK1 Q9Y2Q3 2/20 0.50
LMNA P02545 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
TSHR P16473 1/20 0.46
NFKB1 P19838 1/20 0.46
PMP22 Q01453 1/20 0.46
TET2 Q6N021 2/20 0.42
KDM4A O75164 1/20 0.42
KDM4C Q9H3R0 1/20 0.42
KDM2A Q9Y2K7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11662973 0.93 FOLH1 (0.70) FOLH1RNPEPENPEPGSTK1LMNA
SCHEMBL10963493 0.91 FOLH1 (0.67) FOLH1RNPEPENPEPGSTK1LMNA
SCHEMBL28725208 0.91 FOLH1 (0.67) FOLH1RNPEPENPEPGSTK1LMNA
SCHEMBL10536329 0.91 FOLH1 (0.67) FOLH1RNPEPENPEPGSTK1LMNA
SCHEMBL5024155 0.91 FOLH1 (0.67) FOLH1RNPEPENPEPGSTK1LMNA
SCHEMBL6896569 0.91 FOLH1 (0.67) FOLH1RNPEPENPEPGSTK1LMNA
SCHEMBL1874484 0.84 FOLH1 (1.00) FOLH1RNPEPENPEPTET2KDM4A
SCHEMBL1204501 0.84 FOLH1 (1.00) FOLH1RNPEPENPEPTET2KDM4A
SCHEMBL11159608 0.84 RNPEP (0.76) FOLH1RNPEPLMNA
SCHEMBL5476409 0.84 RNPEP (0.68) FOLH1RNPEPENPEPLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119913746-A Antibacterial and deodorant fabric and preparation method thereof 常州市大尧纺织加工有限公司 2025-05-02 CN claimed
CN-119913746-A Antibacterial and deodorant fabric and preparation method thereof 常州市大尧纺织加工有限公司 2025-05-02 CN disclosed
US-10251392-B2 Antimicrobial devices and compositions AVENT, INC. (US) 2019-04-09 US disclosed
US-9044515-B2 Chemical conjugates for targeted degradation under reducing conditions UNIVERSITY OF DELAWARE (US) 2015-06-02 US disclosed
US-20130244975-A1 CHEMICAL CONJUGATES FOR TARGETED DEGRADATION UNDER REDUCING CONDITIONS UNIVERSITY OF DELAWARE (US) 2013-09-19 US disclosed
CN-102783499-A Antimicrobial devices and compositions ACRYMED INC 2012-11-21 CN disclosed
CN-101010004-B Antimicrobial devices and compositions KIMBERLY CLARK CO 2012-10-03 CN disclosed
US-20090035342-A1 Antimicrobial Devices and Compositions AVANOS MEDICAL SALES, LLC 2009-02-05 US disclosed
US-7312266-B2 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers THE COLLEGE OF WILLIAM AND MARY (US) 2007-12-25 US disclosed
CN-101010004-A Antimicrobial devices and compositions ACRYMED INC (US) 2007-08-01 CN disclosed
EP-1521803-A2 ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS The College of William and Mary (US) 2005-04-13 EP disclosed
US-20050049307-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers COLLEGE OF WILLIAM AND MARY, THE 2005-03-03 US disclosed
US-20040220310-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers THE COLLEGE OF WILLIAM AND MARY 2004-11-04 US disclosed
US-6762231-B2 MERCAPTAN-CONTAINING ALIPHATIC DIESTER UTILIZED FOR HALOGEN-CONTAINING POLYMERS, ESPECIALLY POLY(VINYL CHLORIDE); THE COLLEGE OF WILLIAM AND MARY 2004-07-13 US disclosed
US-6747081-B2 FOR DISCOLORATION INHIBITON OF HALOPOLYMERS SUCH AS POLYVINYL CHLORIDE POLY(VINYLIDENE CHLORIDE), POLY(VINYL BROMIDE), POLY(VINYLIDENE BROMIDE), CHLORINATED POLY(VINYL CHLORIDE), CHLORINATED POLYETHYLENE, CHLORINATED RUBBER THE COLLEGE OF WILLIAM AND MARY 2004-06-08 US disclosed
WO-2003106550-A2 ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS THE COLLEGE OF WILLIAM AND MARY (US) 2003-12-24 WO disclosed
US-20030220429-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers COLLEGE OF WILLIAM AND MARY, THE 2003-11-27 US disclosed
US-20030055141-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers COLLEGE OF WILLIAM AND MARY, THE 2003-03-20 US disclosed
US-20020115769-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers THE COLLEGE OF WILLIAM & MARY (US) 2002-08-22 US disclosed
WO-2002048250-A2 ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS THE COLLEGE OF WILLIAM AND MARY (US) 2002-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049307-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers TST, LANCL1, TTPA FOLH1 4713/4885RNPEP 4343/4885ENPEP 2331/4885
US-10251392-B2 Antimicrobial devices and compositions AAAS, AOC1, COL14A1 FOLH1 2817/4885RNPEP 1908/4885ENPEP 1041/4885
US-20090035342-A1 Antimicrobial Devices and Compositions AAAS, AOC1, COL14A1 FOLH1 2817/4885RNPEP 1908/4885ENPEP 1041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.