Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | APAF1 | O14727 | 2/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29662059 | 1.00 | MAPT (0.58) | MAPTKDM4EGRM5KCNH2POLB | |
| SCHEMBL14127412 | 1.00 | MAPT (0.58) | MAPTKDM4EGRM5KCNH2POLB | |
| SCHEMBL29923695 | 0.84 | NCF1 (0.56) | MAPTKDM4EGRM5KCNH2CYP3A4 | |
| SCHEMBL244384 | 0.84 | NCF1 (0.56) | MAPTKDM4EGRM5KCNH2CYP3A4 | |
| SCHEMBL9376922 | 0.83 | HTT (0.53) | MAPTKDM4EGRM5KCNH2POLB | |
| SCHEMBL6180305 | 0.83 | CYP19A1 (0.47) | MAPTKDM4EGRM5KCNH2POLB | |
| SCHEMBL27297374 | 0.83 | CYP3A4 (0.50) | MAPTKDM4EGRM5KCNH2POLB | |
| SCHEMBL30976614 | 0.82 | NCF1 (0.54) | MAPTKDM4EGRM5KCNH2CYP3A4 | |
| SCHEMBL8347393 | 0.79 | MAPT (0.50) | MAPTKDM4EPOLBCYP3A4MEN1 | |
| Formaldehyde SCHEMBL28759854 | 0.78 | NCF1 (0.50) | MAPTKDM4EGRM5KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 744 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102494-B | Triphenylamine derivative and preparation method thereof, photochromic thin-film material and preparation method and application thereof | 广东工业大学 | 2025-06-03 | — | — | CN | claimed |
| CN-114105984-B | Method for preparing indolizine type corrosion inhibitor | 中国石油大学(华东) | 2023-08-25 | — | — | CN | claimed |
| CN-112250628-B | Method for preparing tetrahydroquinoline compound by catalytic hydrogenation of ruthenium catalyst | 上海应用技术大学 | 2022-07-08 | — | — | CN | claimed |
| CN-110229102-B | 2-alkylated quinoline, derivative and synthetic method thereof | 湘潭大学 | 2022-05-17 | — | — | CN | claimed |
| CN-112375037-B | Synthetic method of 3-amino-5-bromoquinoline | 苏州康润医药有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-114105984-A | Preparation method of indolizine corrosion inhibitor | 中国石油大学(华东) | 2022-03-01 | — | — | CN | claimed |
| CN-114014858-A | Process for preparing polysubstituted indolizine derivatives | 淮阴师范学院 | 2022-02-08 | — | — | CN | claimed |
| CN-111334066-B | 640nm excited near-infrared fluorescent dye and preparation method thereof | 中国科学院大连化学物理研究所 | 2021-12-10 | — | — | CN | claimed |
| CN-112375037-A | Synthetic method of 3-amino-5-bromoquinoline | 苏州康润医药有限公司 | 2021-02-19 | — | — | CN | claimed |
| CN-112250628-A | Method for preparing tetrahydroquinoline compound by catalytic hydrogenation of ruthenium catalyst | 上海应用技术大学 | 2021-01-22 | — | — | CN | claimed |
| CN-111334066-A | 640nm excited near-infrared fluorescent dye and preparation method thereof | 中国科学院大连化学物理研究所 | 2020-06-26 | — | — | CN | claimed |
| CN-110229102-A | 2- is alkylated quinoline, derivative and its synthetic method | 湘潭大学 | 2019-09-13 | — | — | CN | claimed |
| WO-2015095305-A1 | PRODUCTION OF CYCLIC PHOSPHATE, PHOSPHORAMIDATE, THIOPHOSPHATE, AND PHOSPHONATE NUCLEOSIDE COMPOUNDS | IDENIX PHARMACEUTICALS, INC. (US) | 2015-06-25 | — | — | WO | claimed |
| US-6541487-B1 | Administering 5-bromoquinoline, 5-nitroisoquinoline, 8-nitroisoquinoline, 3,4-dihydro-6-hydroxy-2(1H)-quinolone or 1-methylisoquinoline to relax corpus cavernosa smooth-muscle tissue in males or females | R.T. ALAMO VENTURES I, LLC | 2003-04-01 | — | — | US | claimed |
| WO-2002019997-A1 | PDE III INHIBITORS FOR TREATING SEXUAL DYSFUNCTION | CUTLER NEAL R (US) | 2002-03-14 | — | — | WO | claimed |
| US-20260138987-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CONTINEUM THERAPEUTICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| EP-4743457-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 FOR THERAPEUTIC USE | 4M THERAPEUTICS INC. (US) | 2026-05-20 | — | — | EP | disclosed |
| EP-0326328-A2 | Quinoline, quinazoline, and cinnoline derivatives | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |
| US-4396620-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1983-08-02 | — | — | US | disclosed |
| US-4382931-A | 3'-Substituted quinolinium cephalosporins | ELI LILLY AND COMPANY (US) | 1983-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260138987-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CHRM1, CHRM5, CHRM3 | MAPT 2127/4885KDM4E 3909/4885GRM5 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.