Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923695 | 1.00 | NCF1 (0.56) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL30976614 | 0.98 | NCF1 (0.54) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| Formaldehyde SCHEMBL28759854 | 0.94 | NCF1 (0.50) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| Bicarbonate SCHEMBL28387090 | 0.88 | CYP1A2 (0.46) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL29662059 | 0.84 | MAPT (0.58) | NCF1MAPTKDM4EEGFRALDH1A1 | |
| SCHEMBL14127412 | 0.84 | MAPT (0.58) | NCF1MAPTKDM4EEGFRALDH1A1 | |
| SCHEMBL428159 | 0.84 | MAPT (0.58) | NCF1MAPTKDM4EEGFRALDH1A1 | |
| SCHEMBL14919695 | 0.77 | MAPT (0.52) | NCF1LOXL2MAPTKDM4EALDH1A1 | |
| SCHEMBL1227713 | 0.75 | CYP1A2 (0.60) | NCF1LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL29699887 | 0.75 | CYP1A2 (0.60) | NCF1LOXL2HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 699 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039347-A | Diamino diphosphine tetradentate ligand, preparation method thereof and application thereof in Suzuki cross-coupling reaction | 郑州大学 | 2024-11-29 | — | — | CN | claimed |
| CN-118439995-A | Preparation method of pitavastatin intermediate 3- [ 2-cyclopropyl-4- (4-fluorophenyl) -3-quinolyl ] -2-acrolein | 浙江工业大学 | 2024-08-06 | — | — | CN | claimed |
| CN-117945995-A | Alkylated nitrogen-containing heterocyclic compound and preparation method and application thereof | 中国科学院青海盐湖研究所 | 2024-04-30 | — | — | CN | claimed |
| CN-117946000-A | Synthesis method of 1-methyl-2-oxo-1, 2-dihydro-4-quinolinecarboxylic acid methyl ester | 南通大学 | 2024-04-30 | — | — | CN | claimed |
| CN-116178258-B | N-methylaniline quinoline compound and synthetic method and application thereof | 中国医学科学院北京协和医院 | 2023-11-21 | — | — | CN | claimed |
| CN-116178258-A | N-methylaniline quinoline compound and synthetic method and application thereof | 中国医学科学院北京协和医院 | 2023-05-30 | — | — | CN | claimed |
| CN-110229102-B | 2-alkylated quinoline, derivative and synthetic method thereof | 湘潭大学 | 2022-05-17 | — | — | CN | claimed |
| CN-112939857-A | Synthetic method of alkylated quinoline compound | 中国科学院大连化学物理研究所 | 2021-06-11 | — | — | CN | claimed |
| CN-109776406-B | Method for cross coupling of ether compound and quinoline derivative | 湘潭大学 | 2021-05-04 | — | — | CN | claimed |
| CN-110229102-A | 2- is alkylated quinoline, derivative and its synthetic method | 湘潭大学 | 2019-09-13 | — | — | CN | claimed |
| CN-105753838-A | Novel high-regioselectivity amination method of quinoline derivatives | 安阳师范学院 | 2016-07-13 | — | — | CN | claimed |
| CN-102898264-B | Catalytic preparation process for aromatic nitrile or heteroaromatic nitrile | UNIV ZHEJIANG | 2014-07-02 | — | — | CN | claimed |
| EP-0365863-B1 | Novel quinolyloxazole-2-ones useful as proteinkinase C inhibitors | MERRELL DOW PHARMA (US) | 1994-08-17 | — | — | EP | claimed |
| CN-117024411-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| US-20250360145-A1 | CSF-1R INHIBITORS AND USES THEREOF | MYROBALAN THERAPEUTICS INC (US) | 2025-11-27 | — | — | US | disclosed |
| US-20250304558-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2025-10-02 | — | — | US | disclosed |
| US-3974281-A | ANALGESICS, ANTI-PYRETIC AND ANTI-INFLAMMATORY AGENTS | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1976-08-10 | — | — | US | disclosed |
| US-3953453-A | ANTIMALARIAL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-04-27 | — | — | US | disclosed |
| US-3931192-A | Process for piperidine intermediates for quinine, quinidine and analogs thereof | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931193-A | ANTIMALARIA, ANTIARRHYTHMIA INTERMEDIATES | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250360145-A1 | CSF-1R INHIBITORS AND USES THEREOF | CSF1R, CSF3R, IL1RN | NCF1 83/4885LOXL2 1962/4885HTR1A 3696/4885 |
| US-20250304558-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | SLC6A11, SCN1A, KCNH1 | NCF1 1999/4885LOXL2 3194/4885HTR1A 3303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.