Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 2/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4282988 | 0.84 | HDAC3 (0.51) | HDAC3HDAC8NCOR2L3MBTL1TAS2R8 | |
| SCHEMBL4282959 | 0.83 | TAS2R8 (0.63) | KMT2AHDAC3HDAC8NCOR2L3MBTL1 | |
| SCHEMBL4279784 | 0.83 | AR (0.51) | HDAC3HDAC8NCOR2L3MBTL1TAS2R8 | |
| SCHEMBL4286940 | 0.81 | KMT2A (0.51) | KMT2APGRARALDH1A1HPGD | |
| SCHEMBL4287231 | 0.76 | NR1I2 (0.56) | KMT2AHDAC3HDAC8NCOR2L3MBTL1 | |
| SCHEMBL19223061 | 0.75 | L3MBTL1 (0.57) | HDAC3HDAC8NCOR2L3MBTL1TAS2R8 | |
| Hydrochloric Acid SCHEMBL28528265 | 0.74 | L3MBTL1 (0.56) | HDAC3HDAC8NCOR2L3MBTL1TAS2R8 | |
| SCHEMBL21183349 | 0.74 | KMT2A (0.50) | KMT2APGRARALDH1A1HPGD | |
| SCHEMBL633995 | 0.74 | KMT2A (0.76) | KMT2APGRARALDH1A1HPGD | |
| SCHEMBL18593075 | 0.72 | HDAC3 (0.64) | KMT2AHDAC3HDAC8NCOR2SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | GSK3B, GSK3A, GSKIP | KMT2A 871/4885HDAC3 6/4885HDAC8 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.