Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.60 |
| ▸ | FNTB | P49356 | 15/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844704 | 0.91 | FNTA (0.72) | FNTAFNTBCNR1CYP3A4PGGT1B | |
| SCHEMBL28782663 | 0.91 | FNTA (0.72) | FNTAFNTBCNR1CYP3A4PGGT1B | |
| SCHEMBL4285788 | 0.87 | FNTA (0.60) | FNTAFNTBCNR1CYP3A4PGGT1B | |
| SCHEMBL4290048 | 0.86 | FNTA (0.58) | FNTAFNTBCNR1CYP3A4PGGT1B | |
| SCHEMBL1682751 | 0.83 | FNTA (0.61) | FNTAFNTBCNR1CYP3A4PGGT1B | |
| SCHEMBL4278951 | 0.80 | FNTA (0.55) | FNTAFNTBCNR1CYP3A4PGGT1B | |
| SCHEMBL4287009 | 0.79 | FNTA (0.56) | FNTAFNTBCYP3A4PGGT1B | |
| SCHEMBL4282437 | 0.79 | FNTA (0.51) | FNTAFNTBCNR1CYP3A4PGGT1B | |
| SCHEMBL4276938 | 0.77 | FNTA (0.61) | FNTAFNTBCNR1CYP3A4PGGT1B | |
| SCHEMBL4562526 | 0.75 | FNTA (1.00) | FNTAFNTBCYP3A4PGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151683-A2 | QUINOLINONE FARNESYL TRANSFERASE INHIBITORS FOR THE TREATMENT OF SYNUCLEINOPATHIES AND OTHER INDICATIONS | LINK MEDICINE CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |